Evidence map›Paper›PMID 40071581›Full record

ArticleAnatomical record (Hoboken, N.J. : 2007)2025

High-resolution 7-Tesla magnetic resonance imaging and post-processing for 3-dimensional reconstruction of the membranous labyrinth in healthy adults.

Joon Soo Kim, Zahra N Sayyid, Diane Jung, Syed Ameen Ahmad, Jintong Li, Adrian Paez, Yinghao Li, Francis Deng, John P Carey, Jun Hua and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Anatomical record (Hoboken, N.J. : 2007), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. The Gut-Ear Axis: From Dysbiosis to Auditory and Vestibular Disorders.International journal of molecular sciences · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Joon Soo KimDepartment of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Zahra N SayyidDepartment of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Diane JungDepartment of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Syed Ameen AhmadDepartment of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Jintong LiDepartment of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Adrian PaezF.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, Maryland, USA.
Yinghao LiF.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, Maryland, USA.
Francis DengRussell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
John P CareyDepartment of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Jun HuaF.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, Maryland, USA.
Bryan K WardDepartment of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID https://orcid.org/0009-0003-1210-5619

Funding

Research Training in Otolaryngology ProgramR25DC021243 · NIDCD · JOHNS HOPKINS UNIVERSITY · PI John Patrick Carey, Amanda M. Lauer · 2024 to 2026
$1.2M
HIGH FIELD MRI AND THE LABYRINTH: VESTIBULAR STIMULATION AND NEW IMAGING TECHNIQUESK23DC018302 · NIDCD · JOHNS HOPKINS UNIVERSITY · PI WARD, BRYAN KEVIN · 2021 to 2025
$991k
NIDCD NIH HHS K23 DC018302NIDCD NIH HHS R25 DC021243
6 · The paper itself

Abstract

The membranous labyrinth of the inner ear is a complex network of endolymph-filled structures critical for auditory and vestibular function. Pathological distension of these spaces, termed endolymphatic hydrops (EH), is associated with disorders such as Ménière's disease (MD). However, diagnosing inner ear pathologies remains challenging due to limitations in traditional imaging techniques, which lack the spatial resolution required to assess these intricate structures. Advances in 7-Tesla (7T) magnetic resonance imaging (MRI) now allow for high-resolution visualization of the inner ear. In this study, we used 7T T2-weighted and delayed post-contrast 3D-FLAIR sequences to improve visualization of the membranous labyrinth. As the inner ear region is particularly challenging for MRI due to severe transmit (B

Indexed as

7T MRIdielectric padsendolymphatic hydropsinner earmembranous labyrinthMeniere's diseasevolumetric analysis

Identifiers

PMID40071581
PMCPMC12355385

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.