ArticleArtificial organs2025
Design of a Soft Robotic Artificial Cardiac Wall.
Article in Artificial organs, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- A Soft Robotic Model for Simulating Heart Valve Disease and Cardiac Interventions.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
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Authors and funding
9 authors.
Funding
Abstract
backgroundIn cardiovascular engineering, the recent introduction of soft robotic technologies sheds new light on the future of implantable cardiac devices, enabling the replication of complex bioinspired architectures and motions. To support human heart function, assistive devices and total artificial hearts have been developed. However, the system's functionality, hemocompatibility, and overall implantability are still open challenges.
methodsHere, the design of a soft robotic artificial cardiac wall is presented: the action of a bioinspired myocardium of pneumatic McKibben actuators in a double helix is coupled with an engineered passive and deformable endocardial layer made of silicone. The correlation between the helix angle of the actuators and the ejection fraction of the artificial cardiac wall was preliminarily studied with a simplified analytical model. A FEM model was introduced to represent the complex deformation of the endocardial layer during the actuation of the cardiac wall.
resultsExperimental tests report an ejection fraction of 68%, i.e., 77.2 ± 0.4 mL against 90 mmHg, satisfying the minimum physiological requirements and, therefore, proving the concept's functionality.
conclusionsThe conceived device paves the way for a new generation of innovative approaches where engineered bioinspiration might be the key to future artificial cardiac pumps that could support or even substitute the human failing heart.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.