Evidence map›Paper›PMID 40071432›Full record

ReviewRheumatology (Oxford, England)2025

Translational approaches to the study of eosinophils in vasculitis.

Allyson Egan, Paneez Khoury

Abstract readReview
In one paragraph

Review in Rheumatology (Oxford, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Allyson EganDepartment of Nephrology, Trinity Health Kidney Centre, Tallaght University Hospital, Dublin, Ireland.ORCID 0000-0003-3867-816X
Paneez KhouryLaboratory of Parasitic Diseases, Human Eosinophil Section, National Institute of Allergy and Infectious Diseases, National Institute of Health, Bethesda, MD, USA.ORCID 0000-0003-1800-0079

Funding

AstraZenecaNational Institutes of Allergic and Infectious DiseasesNHLBI NIH HHSNIH
6 · The paper itself

Abstract

Eosinophil basic biology, including immunoregulatory functions, plays a complex role in a myriad of disorders where eosinophils play a role. Established in vivo and in vitro models and novel emerging techniques for studying eosinophils are integral to parsing the involvement of eosinophils in the pathogenesis of disorders including vasculitis. Knowledge of translational approaches from eosinophil-associated diseases and their application to eosinophilic vasculitis are highlighted. It is becoming increasingly evident that the roles of eosinophils in disease are complex. The use of targeted biological therapies and machine learning has the potential to reveal the contribution of eosinophils in disease pathology.

Indexed as

EosinophiliaEosinophilsTranslational Research, BiomedicalVasculitisAnimalsHumansclinical trialdegranulationeosinophilIL-5 therapeutics

Identifiers

PMID40071432
PMCPMC11897705

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.