ArticleActas espanolas de psiquiatria2025
Analysis of the Correlation between Frailty Index, Clinical Characteristics, Use of Anti-Epileptic Drug, and Prognosis in Elderly Patients with Epilepsy.
Article in Actas espanolas de psiquiatria, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEpilepsy is a common neurological disorder among the elderly, often leading to significant morbidity. Therefore, it is necessary to study the correlation between the frailty index, clinical characteristics of epilepsy, use of anti-epileptic drug, and the prognosis of elderly patients with epilepsy.
methodsThis retrospective study included 106 elderly patients with epilepsy who were treated at the Affiliated Mindong Hospital, Fujian Medical University, China, between January 2018 and December 2022. Based on the severity of the prognosis, the seizures were classified into the major seizure group (tonic-clonic), minor seizure group (absence, myoclonus, clonus, tonic, atonic and partial seizures), and no seizure group. Furthermore, the relationship between the frailty index, clinical characteristics, use of epilepsy drugs, and the degree of epileptic seizures was assessed using the Logistic regression analysis.
resultsUnivariate analysis indicated that older age (p < 0.001), longer disease duration (p = 0.009), and the presence of comorbid conditions such as diabetes (p = 0.002) and coronary heart disease (p < 0.001) were all associated with seizure severity. Additionally, frailty was significantly related to seizure severity, with the non-frailty group having fewer major seizures compared to the pre-frailty and frailty groups (p < 0.001). Similarly, regular medication use (p < 0.001) and the number of drugs taken (p < 0.001) were significant factors, with irregular medication use and single-drug regimens being more common in patients with more severe seizures. Multivariate Logistic regression analysis indicated that a higher frailty index (p = 0.033), age over 70 years (p = 0.015), longer disease duration (p = 0.003), the presence of coronary heart disease (p < 0.001), and regular medication use (p = 0.022) were all significantly associated with more severe seizures.
conclusionFrailty index, age, disease duration, coronary heart disease, and regular medication are related to the prognosis of elderly patients with epilepsy. These findings highlight the significance of comprehensive management strategies to improve clinical outcomes in this group of patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.