Evidence map›Paper›PMID 40071342›Full record

SynthesisBiomarkers in medicine2025

Red cell distribution width related to the severity of the disease in patients with AECOPD.

Yiben Huang, Jianing Wang, Siyao Chen, Zicong Dai, Xuanyang Chen, Xinran Li, Ruizi Xu, Beibei Yu, Chunyan Liu, Xianjing Chen and 3 more

Abstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Biomarkers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yiben HuangDepartment of Respiratory and Critical Medicine, The Third Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Jianing WangThe First School of Medicine, School of Information and Engineering, Wenzhou Medical University, Wenzhou, China.
Siyao ChenThe First School of Medicine, School of Information and Engineering, Wenzhou Medical University, Wenzhou, China.
Zicong DaiThe First School of Medicine, School of Information and Engineering, Wenzhou Medical University, Wenzhou, China.
Xuanyang ChenThe Second School of Medicine, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Xinran LiThe Second School of Medicine, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Ruizi XuRenji College, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Beibei YuDepartment of Respiratory and Critical Medicine, The Third Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Chunyan LiuDepartment of Respiratory and Critical Medicine, The Third Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Xianjing ChenDepartment of Respiratory and Critical Medicine, The Third Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Pengfei ZhangDepartment of Respiratory and Critical Medicine, The Third Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Yage XuDepartment of Respiratory and Critical Medicine, The Third Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Xiaodiao ZhangDepartment of Respiratory and Critical Medicine, The Third Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThis research aims to elucidate the association between red cell distribution width (RDW) and the severity of acute exacerbations of chronic obstructive pulmonary disease (AECOPD). PATIENTS &

methodsThis retrospective study enrolled patients with AECOPD and healthy controls. A comprehensive meta-analysis was further conducted by systematically searching PubMed, Embase, and the Cochrane Library up to 27 April 2023.

resultsUnivariate logistic regression analysis indicated that elevated RDW levels were significantly associated with AECOPD (

conclusionElevated RDW levels exhibit a linear positive correlation with AECOPD severity, further supported by meta-analysis.

Indexed as

Erythrocyte IndicesErythrocytesPulmonary Disease, Chronic ObstructiveAgedBiomarkersFemaleHumansMaleMiddle AgedRetrospective StudiesSeverity of Illness IndexBiomarkersBODEchronic obstructive pulmonary diseaseFEV1%meta-analysisprognosisRed cell distribution widthseverity

Identifiers

PMID40071342
PMCPMC11916365

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.