Evidence map›Paper›PMID 40071314›Full record

ArticleArtificial organs2025

Enhancing Kidney Quality Assessment: Power Doppler During Normothermic Machine Perfusion.

Yitian Fang, Anton V Nikolaev, Jeroen Essers, Gisela Ambagtsheer, Marian C Clahsen-van Groningen, Robert C Minnee, Ron W F de Bruin, Gijs van Soest

Abstract read
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In one paragraph

Article in Artificial organs, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yitian FangDivision of HPB and Transplant Surgery, Department of Surgery, Transplant Institute, Erasmus Medical Center, Rotterdam, the Netherlands.ORCID https://orcid.org/0000-0002-5523-9794
Anton V NikolaevCardiovascular Institute, Thorax Center, Department of Cardiology, Erasmus Medical Center, Rotterdam, the Netherlands.
Jeroen EssersDepartment of Molecular Genetics, Cancer Genomics Center, Erasmus Medical Center, Rotterdam, the Netherlands.
Gisela AmbagtsheerDivision of HPB and Transplant Surgery, Department of Surgery, Transplant Institute, Erasmus Medical Center, Rotterdam, the Netherlands.
Marian C Clahsen-van GroningenDepartment of Pathology and Clinical Bioinformatics, Erasmus Medical Center, Rotterdam, the Netherlands.
Robert C MinneeDivision of HPB and Transplant Surgery, Department of Surgery, Transplant Institute, Erasmus Medical Center, Rotterdam, the Netherlands.
Ron W F de BruinDivision of HPB and Transplant Surgery, Department of Surgery, Transplant Institute, Erasmus Medical Center, Rotterdam, the Netherlands.
Gijs van SoestCardiovascular Institute, Thorax Center, Department of Cardiology, Erasmus Medical Center, Rotterdam, the Netherlands.

Funding

Nederlandse Organisatie voor Wetenschappelijk Onderzoek
6 · The paper itself

Abstract

objectivesMarginal donor kidneys are increasingly used for transplantation to overcome organ shortage. This study aims to investigate the additional value of Power Doppler (PD) imaging in kidney quality assessment during normothermic machine perfusion (NMP).

methodsPorcine kidneys (n = 22) retrieved from a local slaughterhouse underwent 2 h of NMP. Based on creatinine clearance (CrCl) and oxygen consumption (VO

resultsFI and VFI moderately correlated with CrCl (r = 0.537, p < 0.0001; r = 0.536, p < 0.0001, respectively), while VI strongly correlated with VO

conclusionsPD metrics strongly correlate with renal viability and effectively differentiate kidneys with higher and lower functionality during NMP. PD imaging can be a valuable alternative to RBF during NMP for kidney quality assessment.

Indexed as

KidneyKidney TransplantationOrgan PreservationPerfusionUltrasonography, DopplerAnimalsOxygen ConsumptionRenal CirculationSwineDoppler ultrasoundexperimental animal modelkidney functionquality assessment

Identifiers

PMID40071314
PMCPMC12179758

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.