Evidence map›Paper›PMID 40071159›Full record

SynthesisJournal of medicine and life2025

Pathogenic variants in

Flor Daniela Alday-Montañez, Daniel Dickens-Terrazas, Gloria Erika Mejia-Carmona, Elisa Robles-Escajeda, Robert Arthur Kirken, Alfonso Enrique Bencomo-Alvarez, Victor Josue Carrasco-Urrutia, Naun Lobo-Galo, Luis Fernando Plenge-Tellechea, Ángel Gabriel Diaz-Sanchez and 1 more

Abstract readSystematic Review
In one paragraph

Synthesis in Journal of medicine and life, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Identification and Computational Analysis ofMedical sciences (Basel, Switzerland) · 2026
    Article
  2. Article
  3. Identification and Computational Analysis ofMedical sciences (Basel, Switzerland) · 2025
    Article
  4. miRNA expression haplotype in Hispanics with endometriosis.Frontiers in reproductive health · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Flor Daniela Alday-MontañezDepartment of Chemical-Biological Sciences, Autonomous University of Ciudad Juarez, Ciudad Juarez, Chihuahua, Mexico.
Daniel Dickens-TerrazasIMSS, Zone Hospital Number 6, Ciudad Juarez, Chihuahua, Mexico.
Gloria Erika Mejia-CarmonaDepartment of Chemical-Biological Sciences, Autonomous University of Ciudad Juarez, Ciudad Juarez, Chihuahua, Mexico.
Elisa Robles-EscajedaDepartment of Biological Sciences, The Border Biomedical Research Center, The Cellular Characterization and Biorepository Core Facility, The University of Texas, El Paso, Texas, USA.
Robert Arthur KirkenDepartment of Biological Sciences, The Border Biomedical Research Center, The Cellular Characterization and Biorepository Core Facility, The University of Texas, El Paso, Texas, USA.
Alfonso Enrique Bencomo-AlvarezDepartment of Host-Microbe Interactions, St. Jude Children's Research Hospital, Memphis, TN, USA.
Victor Josue Carrasco-UrrutiaEndofem, Ciudad Juarez, Chihuahua, Mexico.
Naun Lobo-GaloDepartment of Chemical-Biological Sciences, Autonomous University of Ciudad Juarez, Ciudad Juarez, Chihuahua, Mexico.
Luis Fernando Plenge-TellecheaDepartment of Chemical-Biological Sciences, Autonomous University of Ciudad Juarez, Ciudad Juarez, Chihuahua, Mexico.
Ángel Gabriel Diaz-SanchezDepartment of Chemical-Biological Sciences, Autonomous University of Ciudad Juarez, Ciudad Juarez, Chihuahua, Mexico.
Alejandro Martínez-MartínezDepartment of Chemical-Biological Sciences, Autonomous University of Ciudad Juarez, Ciudad Juarez, Chihuahua, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast and ovarian cancers are significant global health challenges, with inherited variations in breast cancer gene 1 (

Indexed as

BRCA1 ProteinBRCA2 ProteinBreast NeoplasmsGenetic Predisposition to DiseaseOvarian NeoplasmsDatabases, GeneticFemaleHumansMexicoPolymorphism, Single NucleotideBRCA1 ProteinBRCA1 protein, humanBRCA2 ProteinBRCA2 protein, humanBARD1, BRCA1-associated RING domain protein-1BC, Breast cancerBRCA1, Breast Cancer Susceptibility Gene 1BRCA2, Breast Cancer Susceptibility Gene 2breast cancerCR, mutation-specific cluster regionsfounder effectgenetic variationHBOC, hereditary breast and ovarian cancer syndrome (HBOC)HRR, Homologous Recombination Repair pathwayMexican populationMLPA, multiplex ligation-dependent probe amplificationOC, ovarian cancerovarian cancerPALB2, Partner and Localizer of BRCA2RAD-51, DNA repair protein RAD-51 homolog 1SNVs, Single Nucleotide variantsTCGA, The Cancer Genome AtlasTNBC, triple-negative breast cancer

Identifiers

PMID40071159
PMCPMC11891617

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.