Evidence map›Paper›PMID 40071146›Full record

ArticleiScience2025

Fine-tuning of Wnt signaling by RNA surveillance factor Smg5 in the mouse craniofacial development.

Shicheng Zhu, Suman Huo, Weiran He, Caiyan Huang, Jiannan Zhang, Xiaoning Jiang, Yeqing Qian, Chengyan Chen, Zhong-Min Dai, Xueqin Yang and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  5. International journal of molecular sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Shicheng ZhuCollege of Life and Environmental Sciences, Zhejiang Key Laboratory of Organ Development and Regeneration, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.
Suman HuoCollege of Life and Environmental Sciences, Zhejiang Key Laboratory of Organ Development and Regeneration, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.
Weiran HeCollege of Life and Environmental Sciences, Zhejiang Key Laboratory of Organ Development and Regeneration, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.
Caiyan HuangCollege of Life and Environmental Sciences, Zhejiang Key Laboratory of Organ Development and Regeneration, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.
Jiannan ZhangCollege of Life and Environmental Sciences, Zhejiang Key Laboratory of Organ Development and Regeneration, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.
Xiaoning JiangSchool of Basic Medical Sciences, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.
Yeqing QianWomen's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310006, China.
Chengyan ChenState Key Laboratory of Microbial Technology, Shandong University, Qingdao 250100, China.
Zhong-Min DaiCollege of Life and Environmental Sciences, Zhejiang Key Laboratory of Organ Development and Regeneration, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.
Xueqin YangCollege of Life and Environmental Sciences, Zhejiang Key Laboratory of Organ Development and Regeneration, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.
Mengsheng QiuCollege of Life and Environmental Sciences, Zhejiang Key Laboratory of Organ Development and Regeneration, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.
Tangliang LiSchool of Basic Medical Sciences, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.
Xiao-Jing ZhuCollege of Life and Environmental Sciences, Zhejiang Key Laboratory of Organ Development and Regeneration, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The specific roles of nonsense-mediated mRNA decay (NMD), a translation-dependent RNA quality control mechanism that degrades mRNAs containing premature termination codons (PTCs), in mammalian craniofacial development have remained unclear. Here, we show that knockout of the essential NMD factor

Indexed as

Cell biologyDevelopmental biologyPathophysiology

Identifiers

PMID40071146
PMCPMC11894330

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.