Evidence map›Paper›PMID 40070892›Full record

ArticleJAC-antimicrobial resistance2025

The environmental impact of intravenous antimicrobial therapies: a comparison of OPAT and inpatient administration care pathways.

Ann Cole, Julie Aspin, Steven Laird, Flavio Acri, Saori Galley, Michael Collins

Abstract read
In one paragraph

Article in JAC-antimicrobial resistance, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ann ColeGovernment Affairs and Market Access, Baxter Healthcare Limited, Compton, UK.
Julie AspinEHS and Sustainability, Baxter Healthcare Limited, Compton, UK.
Steven LairdMicrobiology, University Hospitals Coventry and Warwickshire (UHCW) NHS Trust, Coventry, UK.
Flavio AcriMarketing, Baxter Healthcare Limited, Compton, UK.
Saori GalleyConsulting, Environmental Resources Management (ERM), London, UK.
Michael CollinsConsulting, Environmental Resources Management (ERM), London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: The urgent global threats of the climate crisis and antimicrobial resistance have the potential to be addressed in part by increasing the use of outpatient antimicrobial therapy (OPAT). Our study aimed to appraise the environmental impact of three commonly used OPAT pathways, and the traditional inpatient model of IV antimicrobial therapy. Methods: We assessed the CO Results: We found that the administration of IV antibiotics in hospital is associated with a substantial environmental impact compared to OPAT. When OPAT is self-administered in the patient's home, we discovered a CO Conclusions: Our study demonstrates that using OPAT reduces the environmental impact of delivering antimicrobial therapy compared to inpatient treatment. As it is delivered away from the hospital setting, it may also reduce the risks to health associated with inpatient care. While we have shown that the reduction in CO

Identifiers

PMID40070892
PMCPMC11894253

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.