Evidence map›Paper›PMID 40070870›Full record

ArticleMaterials today. Bio2025

Size-dependent interactions between calciprotein particles and vascular endothelium.

Zeping Zhang, Xinyue Wang, Caihao Huang, Meixia Wang, Wei Cui, Liang Hao, Rui Yang, Hong-Hui Wang, Xing Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials today. Bio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zeping ZhangInstitute of Metal Research, Chinese Academy of Sciences, Shenyang, Liaoning 110016, China.
Xinyue WangInstitute of Metal Research, Chinese Academy of Sciences, Shenyang, Liaoning 110016, China.
Caihao HuangInstitute of Metal Research, Chinese Academy of Sciences, Shenyang, Liaoning 110016, China.
Meixia WangState Key Laboratory of Chemo/Bio-Sensing and Chemometrics, College of Biology, Hunan University, Changsha, Hunan 410082, China.
Wei CuiInstitute of Metal Research, Chinese Academy of Sciences, Shenyang, Liaoning 110016, China.
Liang HaoSchool of Forensic Medicine, China Medical University, Shenyang, Liaoning 110026, China.
Rui YangInstitute of Metal Research, Chinese Academy of Sciences, Shenyang, Liaoning 110016, China.
Hong-Hui WangState Key Laboratory of Chemo/Bio-Sensing and Chemometrics, College of Biology, Hunan University, Changsha, Hunan 410082, China.
Xing ZhangInstitute of Metal Research, Chinese Academy of Sciences, Shenyang, Liaoning 110016, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The underlying mechanisms governing the interactions between nanoparticles and vascular endothelial barrier remain largely unexplored, which is crucial for the optimal design of nanoparticles for clinical applications. In this study, the size-dependent interactions between calciprotein particles (CPPs) and endothelial cells (ECs) were investigated using a rat model of chronic kidney disease (CKD) induced by 5/6 nephrectomy. Two primary types of CPP1 were studied: small-sized CPP1 (S-CPP1, <50 nm) and larger CPP1 (L-CPP1, <100 nm), detected three and five weeks post-surgery, respectively. By adjusting the amounts of Ca

Indexed as

Biomimetic synthesisCalciprotein nanoparticlesChronic kidney diseaseEndothelium

Identifiers

PMID40070870
PMCPMC11894339

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.