ArticleHorticulture research2025
Flavonoids as key players in cold tolerance: molecular insights and applications in horticultural crops.
Article in Horticulture research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed.
- Cold-induced anthocyanin regulation in horticultural crops: mechanistic basis, trade-offs, and decision-driven temperature management in plant factories.Horticulture research · 2026Review
- Overview of molecular mechanisms underlying stress responses; signaling pathways and secondary metabolite synthesis in plants.Plant molecular biology · 2026Review
- Article
- Integrated transcriptomic and metabolomic analysis reveals key pathways and metabolites underlying cold tolerance in passion fruit.Horticulture research · 2026Article
- Germplasm Screening and Transcriptome Profiling Identify Phenylpropanoid Biosynthesis-Related PAL Candidate Genes Associated with Freezing Tolerance in Potato.Biomolecules · 2026Article
- NtWHY1 negatively regulates tobacco cold tolerance via interfering with flavonoid biosynthesis.Plant cell reports · 2026Article
- Integrated Transcriptomic and Metabolomic Analysis Reveals Molecular Responses Associated with Foliar Selenium Treatment Under Cold Stress in Rapeseed (International journal of molecular sciences · 2026Article
- Effects of Different Temperatures on Flavonoid Secondary Metabolites and Antioxidant Activities ofAntioxidants (Basel, Switzerland) · 2026Article
- The CsBES1-14-CsCOR413 module mediated by brassinolide positively regulates cold resistance in tea plant.Horticulture research · 2026Article
- Chromosome-scale genome of Myriophyllum spicatum unveils the role of allohexaploidy in driving aquatic adaptation and widespread invasion.The Plant journal : for cell and molecular biology · 2026Article
- The MdICE1/MdFAMA-MdTYDC Transcriptional Module Confers Cold Tolerance by Regulating Dopamine Metabolism in Apple.Plant biotechnology journal · 2026Article
- Calmodulin-Like Protein MfCML50 Interacts With Carveol Dehydrogenase in Medicago falcata to Regulate Cold Tolerance Through Mediating ROS Homeostasis.Plant biotechnology journal · 2026Article
- Integrated Transcriptomic and Metabolomic Analyses Provide Insights into the Response of Red Clover (International journal of molecular sciences · 2026Article
- The Transcription Factors NFYA1 and GBF3 Jointly Regulate CHS2 to Promote Tangeretin Accumulation and Cold Tolerance in Citrus.Plant biotechnology journal · 2026Article
- Transcriptome mining of key genes involved in seasonal changes of total flavonoids inFrontiers in plant science · 2026Article
- Bio-stimulants enhance cold tolerance in tobacco through antioxidant defense and photosynthetic regulation.Frontiers in microbiology · 2026Review
- Cold-tolerant bacteria from alpine Rosaceae plants modulate transcriptional responses of apple and strawberry plantlets to freezing stress.Frontiers in plant science · 2026Article
- Integrated physiological, transcriptomic and metabolomic analysis reveals differential cold response in wheat seedlings across varieties.Frontiers in plant science · 2026Article
- Cultivation substrates alter plant metabolic profiles with concomitant impacts on herbivore performance.Frontiers in microbiology · 2026Article
- Biodiversity-Driven Natural Products and Bioactive Metabolites.Plants (Basel, Switzerland) · 2025Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cold stress profoundly affects the growth, development, and productivity of horticultural crops. Among the diverse strategies plants employ to mitigate the adverse effects of cold stress, flavonoids have emerged as pivotal components in enhancing plant resilience. This review was written to systematically highlight the critical role of flavonoids in plant cold tolerance, aiming to address the increasing need for sustainable horticultural practices under climate stress. We provide a comprehensive overview of the role of flavonoids in the cold tolerance of horticultural crops, emphasizing their biosynthesis pathways, molecular mechanisms, and regulatory aspects under cold stress conditions. We discuss how flavonoids act as antioxidants, scavenging reactive oxygen species (ROS) generated during cold stress, and how they regulate gene expression by modulating stress-responsive genes and pathways. Additionally, we explore the application of flavonoids in enhancing cold tolerance through genetic engineering and breeding strategies, offering insights into practical interventions for improving crop resilience. Despite significant advances, a research gap remains in understanding the precise molecular mechanisms by which specific flavonoids confer cold resistance, especially across different crop species. By addressing current knowledge gaps, proposing future research directions and highlighting implications for sustainable horticulture, we aim to advance strategies to enhance cold tolerance in horticultural crops.
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Registered trials
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