ArticleObesity (Silver Spring, Md.)2025
Fetal exposure to gestational diabetes severity and postnatal infant feeding in the first year of life associated with preadolescent obesity: a prospective cohort.
Article in Obesity (Silver Spring, Md.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Cumulative Household Food Insecurity Is Associated with Adverse Eating Behaviors Among Youth Exposed to Gestational Diabetes in Utero.Nutrients · 2026Article
- Breastfeeding Intensity and Duration and Growth Trajectories in GDM Exposed Infants: The SWIFT Study.Pediatric obesity · 2026Article
- Persistent Food Insecurity and Overweight/Obesity Risk in Offspring of Individuals With Gestational Diabetes.Pediatric obesity · 2026Observational
- Dietary macronutrient substitutions and cardiometabolic outcomes in children with and without gestational diabetes exposure: a cross-sectional analysis.The American journal of clinical nutrition · 2026Article
- Midchildhood Obesity After Exposure to Gestational Diabetes Mellitus: The SWIFT Study in Youth.Diabetes care · 2026Article
- Diabetes and women's health.Journal of diabetes investigation · 2025Review
Corrections and comments
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Authors and funding
14 authors.
Funding
Abstract
objectiveThis study sought to evaluate the distinct impact of fetal exposure to gestational diabetes (GDM) severity, as well as the impact of infant breastfeeding (BF) and sugary beverage intake, on preadolescent overweight and obesity, accounting for other established risk factors.
methodsThis analysis included 850 mother-infant dyads exposed to GDM who reported monthly infant BF duration and intensity, as well as sugary beverage intake (sugar-sweetened beverages [SSB] and 100% fruit juice [FJ]) during the first year of life, BMI measured at ages 6 to 11 years, and GDM severity variables (i.e., diagnosis time, treatment, and glycemic control). Preadolescent weight and height from electronic health records classified the following BMI percentiles: normal weight, <85th percentile (referent); overweight (85th to <95th percentile); obesity (≥95th percentile); moderate obesity (100 to <120% of 95th percentile); and severe obesity (≥120% of 95th percentile). Log-binomial regression models estimated adjusted relative risk (aRR) and 95% CI of BMI categories associated with fetal exposure to GDM severity and infant diet (inadequate BF, <6 months or adequate BF, ≥6 months, combined with or without SSB/FJ intake).
resultsAmong preadolescents, 17.6% had overweight, 18.2% had moderate obesity, and 7.6% had severe obesity. Compared with adequate BF with no SSB/FJ, aRR (95% CI) of developing obesity was 1.55 (95% CI: 1.05-2.30) for inadequate BF with SSB/FJ intake and 1.50 (95% CI: 1.01-2.21) for adequate BF with SSB/FJ intake, independent of GDM severity and covariates. The aRR (95% CI) of developing severe obesity was 3.80 (95% CI: 1.55-9.29) for inadequate BF with SSB/FJ intake versus adequate BF without SSB/FJ intake.
conclusionsBF adequacy and avoidance of sugary beverages in early life are modifiable lifestyle behaviors that may combat preadolescent obesity in infants exposed to GDM, suggesting potential longer-term benefits on child cardiometabolic health.
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