Evidence map›Paper›PMID 40070079›Full record

ArticleAlcohol, clinical & experimental research2025

Identifying family environment profiles in families of children with prenatal alcohol exposure.

Riley J Felicicchia, Matthew T Hyland, Scott C Roesch, Sarah N Mattson

Abstract read
In one paragraph

Article in Alcohol, clinical & experimental research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Assessment of GABANeuroscience letters · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Riley J FelicicchiaCenter for Behavioral Teratology and Department of Psychology, San Diego State University, San Diego, California, USA.
Matthew T HylandCenter for Behavioral Teratology and Department of Psychology, San Diego State University, San Diego, California, USA.
Scott C RoeschDepartment of Psychology, San Diego State University, San Diego, California, USA.
Sarah N MattsonCenter for Behavioral Teratology and Department of Psychology, San Diego State University, San Diego, California, USA.ORCID 0000-0001-8499-9605

Funding

FASD in San Diego and Moscow (U01 Research Project)U01AA014834 · NIAAA · SAN DIEGO STATE UNIVERSITY · PI SARAH N MATTSON WELLER · 2003 to 2026
$12.4M
Alcohol Research in the Science/Practitioner ModelT32AA013525 · NIAAA · SAN DIEGO STATE UNIVERSITY · PI EDWARD P RILEY, ANDREA SPADONI TOWNSEND · 2002 to 2026
$8.4M
Exploring Risk and Resilience Factors in Families of Children with FASD: A Mixed Methods ApproachF31AA031883 · NIAAA · SAN DIEGO STATE UNIVERSITY · PI FELICICCHIA, RILEY JORDAN · 2024 to 2025
$79k
NIAAA NIH HHS F31 AA031883NIAAA NIH HHS F31 AA031883NIAAA NIH HHS T32 AA013525NIAAA NIH HHS U01 AA014834
6 · The paper itself

Abstract

backgroundIndividuals with prenatal alcohol exposure (PAE) may face unique family environments that potentially influence adaptive functioning and behavioral challenges. This study aimed to identify profiles of families of children with PAE based on family characteristics, including cohesion, conflict, and organization, and to examine the relationship between family environment profiles and child outcomes.

methodsData were collected from caregivers of 283 youth (5-17 years) with histories of PAE. Caregivers completed several questionnaires, including the Child Behavior Checklist (CBCL), Vineland Adaptive Behavior Scales (VABS), and Family Environment Scale (FES). Latent profile analysis (LPA) was used to identify profiles in the family environment using three subscales from the FES (Cohesion, Conflict, and Organization). Model fit was determined by comparing 1-, 2-, 3-, 4-, and 5-profile solutions. One-way ANCOVA follow-up tests were conducted to explore differences in adaptive and behavioral functioning across family environment profiles.

resultsThe 4-profile solution was considered the best fit for the data. Interpretation of conditional response probabilities indicated that Profile 1 was defined by low cohesion; Profile 2 was defined by low organization; Profile 3 was defined as high cohesion and organization; and Profile 4 was defined as high conflict. After controlling for race, sex, age, and ethnicity, there were significant profile differences on the Internalizing, Externalizing, and Total Problem Behavior scales of the CBCL. There were no significant differences in adaptive functioning across profiles.

conclusionsThe results of this study highlight the importance of the family environment in understanding the strengths and challenges experienced by children with PAE. Four unique profiles of family environments emerged in families of children with PAE. The high-conflict profile was associated with increased behavioral problems in children. These findings can be used to support families of children with PAE and to identify treatment targets for interventions for children with PAE and their caregivers.

Indexed as

FamilyPrenatal Exposure Delayed EffectsAdaptation, PsychologicalAdolescentAdultChildChild BehaviorChild, PreschoolFamily RelationsFemaleHumansMalePregnancySurveys and Questionnairesbehaviorfamily characteristicsfetal alcohol spectrum disordersprenatal alcohol exposure

Identifiers

PMID40070079
PMCPMC12012878

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.