Evidence map›Paper›PMID 40070028›Full record

Trial reportClinical implant dentistry and related research2025

Moldable and Particulate Bone Material in Alveolar Ridge Preservation: A Multicenter Randomized Controlled Trial.

Yiseul Choi, Jieun Cheong, Yoolbin Song, Jaeyeon Kim, Dae-Young Kang, Hyeon-Seong Ahn, Sanghoon Park, Marco Esposito, Hyun-Seung Shin, Wonse Park

Abstract readRandomized Controlled TrialMulticenter Study
In one paragraph

Trial report in Clinical implant dentistry and related research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Impact of the Buccal Dehiscence Morphotype on the Regenerative Strategy in Immediate Implant Placement.Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yiseul ChoiDepartment of Advanced General Dentistry, Yonsei University College of Dentistry, Seoul, Korea.ORCID https://orcid.org/0000-0001-6283-9686
Jieun CheongDepartment of Advanced General Dentistry, Yonsei University College of Dentistry, Seoul, Korea.ORCID https://orcid.org/0000-0003-0313-2511
Yoolbin SongDepartment of Advanced General Dentistry, Yonsei University College of Dentistry, Seoul, Korea.
Jaeyeon KimDepartment of Advanced General Dentistry, Yonsei University College of Dentistry, Seoul, Korea.ORCID https://orcid.org/0000-0002-0603-619X
Dae-Young KangDepartment of Periodontology, Dankook University College of Dentistry, Cheonan, Korea.
Hyeon-Seong AhnDepartment of Periodontology, Dankook University College of Dentistry, Cheonan, Korea.
Sanghoon ParkDepartment of Advanced General Dentistry, Yonsei University College of Dentistry, Seoul, Korea.
Marco EspositoDental School, Vita-Salute and IRCCS San Raffaele University, Milan, Italy.
Hyun-Seung ShinDepartment of Periodontology, Dankook University College of Dentistry, Cheonan, Korea.
Wonse ParkDepartment of Advanced General Dentistry, Yonsei University College of Dentistry, Seoul, Korea.ORCID https://orcid.org/0000-0002-2081-1156

Funding

MedPark
6 · The paper itself

Abstract

introductionThis study aimed to determine possible histological and radiological differences in alveolar ridge preservation (ARP), using moldable bone versus particulate bone.

methodsAfter tooth extraction, 39 patients (40 teeth) were randomized (1:1) to receive ARP using moldable bone materials (SBX group) or particulate bone materials (PBX group). An absorbable collagen membrane was placed over the graft material and the surgical site was sutured. Cone-beam computed tomography was taken immediately and 5 months after ARP. Bone core samples from the implantation site were obtained for histomorphometric analysis 5 months after ARP.

resultsForty-six patients were screened and 39 of them completed the study. However, one patient who received split-mouth treatment was excluded, resulting in data from 38 patients being analyzed. In radiological evaluation, the changes in midbuccal alveolar bone height at 5 months were -0.753 ± 0.112 and -1.018 ± 0.111 mm in the SBX group and PBX groups, respectively (F = 2.895; p = 0.098; mean difference [MD] 0.265; 95% confidence interval [CI] = -0.051 to 0.582). Changes in the horizontal ridge width were measured at three levels (-1, -3, and -5 mm) below the most coronal aspect of the crest and showed a decrease in both groups, with no significant differences between the groups. The percent new bone area of the SBX group (39.156 ± 2.505) was significantly different from that of the PBX group (22.749 ± 2.476) (F = 22.171; p < 0.001; 95% MD 16.407; CI = 9.333 to 23.481). The percent residual material area was significantly lower in the SBX group (8.973 ± 2.211) compared to the PBX group (15.633 ± 2.186), with an F-statistic of 4.687 and p-value = 0.037 (MD -6.660; 95% CI = -12.904 to -0.415). The percent connective tissue area was 49.743 ± 4.199 and 56.657 ± 4.151 for the groups (F = 1.401; p = 0.245; MD -6.914; 95% CI = -18.773 to 4.944), respectively.

conclusionRadiological and histological results showed that use of moldable bone can achieve similar ARP parameters as those achieved by particulate bone.

trial registrationClinical Research Information Service No. KCT0009560. This randomized clinical trial was not registered before participant recruitment and randomization. (Date of registration: 21/06/2024. https://cris.nih.go.kr/cris/search/detailSearch.do?seq=27272&searchpage=L).

Indexed as

Alveolar Bone LossAlveolar Ridge AugmentationBone SubstitutesBone TransplantationAdultAgedAlveolar ProcessCone-Beam Computed TomographyDental Implantation, EndosseousFemaleHumansMaleMiddle AgedTooth ExtractionBone Substitutesalveolar ridge preservationmoldable boneparticulate bone

Identifiers

PMID40070028
PMCPMC11951245

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.