Evidence map›Paper›PMID 40069933›Full record

ArticleAmerican journal of epidemiology2025

Leveraging the All of Us research program to advance heart, lung, blood, and sleep research.

Meagan G Grant, Gabriel Anaya, Olga Brazhnik, Christian R Gomez, Aaron D Laposky, Lisa Postow, Vandana Sachdev, Xinzhi Zhang, Nicole Redmond

Abstract read
In one paragraph

Article in American journal of epidemiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Meagan G GrantNational Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, United States.ORCID 0000-0002-7218-4772
Gabriel AnayaNational Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, United States.
Olga BrazhnikNational Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, United States.
Christian R GomezNational Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, United States.
Aaron D LaposkyNational Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, United States.
Lisa PostowNational Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, United States.
Vandana SachdevNational Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, United States.
Xinzhi ZhangAgency for Healthcare Research and Quality, U.S. Department of Health and Human Services, Rockville, MD 20857, United States.
Nicole RedmondNational Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent scientific and technological innovations presage a future wherein heart, lung, blood, and sleep (HLBS) health threats are preempted and wherein precision medicine reduces the burden of HLBS disease. The research priorities of the National Heart, Lung, and Blood Institute (NHLBI) Strategic Vision guide Institute activities toward this future. To realize the Strategic Vision, NHLBI has drawn upon its rich resources, including its cohort studies, clinical trial infrastructure, and precision medicine programs. Strategic Vision implementation also requires leveraging datasets of scale and scope expansive enough to deconstruct the complexity of human biology and disease. The large platform of participants and datatypes in the All of Us Research Program (All of Us) facilitates exploration of scientific questions toward improved knowledge, prevention, and management of HLBS conditions. Here, we discuss how utilizing All of Us has stimulated novel HLBS research and provide examples of future research that can be conducted via this platform. Overall, Strategic Vision implementation through All of Us will elucidate how biology, lifestyle, and social and physical environment influence health and disease; deepen understanding of population and individual differences or disparities; and accelerate development, implementation, and dissemination of targeted diagnostic, prevention, and treatment strategies for HLBS conditions.

Indexed as

Biomedical ResearchHumansNational Heart, Lung, and Blood Institute (U.S.)Precision MedicineSleepUnited Statesbiology-lifestyle-environment interactionscardiovascular health and diseasechronic diseasecohort studyelectronic health recordsgenomic dataprecision medicine

Identifiers

PMID40069933
PMCPMC12709128

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.