ArticleBMC medicine2025
Modifications to the National Early Warning Score 2: a Scoping Review.
Article in BMC medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed.
- Inflammatory and Endothelial Dysfunction Biomarkers Predict Severe COVID-19 in Hospitalized Patients: Development of the CCBR Model.Biomedicines · 2026Article
- Dual-score framework: National Early Warning Score 2 and quick Sequential Organ Failure Assessment scores in acute pyelonephritis.World journal of nephrology · 2026Article
- Integration of the National Early Warning Score 2 and the procalcitonin-to-albumin ratio for sepsis prediction in patients with pyogenic liver abscess: a retrospective cohort study.BMC infectious diseases · 2026Article
- Multi-omics reveals regulatory networks and critical early-warning factors for severe disease progression in diabetic patients infected with SARS-CoV-2.Frontiers in immunology · 2026Observational
- Development and Validation of a NEWS2-Enhanced Multivariable Prediction Model for Clinical Deterioration and In-Hospital Mortality in Hospitalized Adults.Medicina (Kaunas, Lithuania) · 2025Article
- Let Our Patients Sleep: A Plea for Common Sense.Neurology. Clinical practice · 2025Article
- Improving prediction accuracy of hospital arrival vital signs using a multi-output machine learning model: a retrospective study of JSAS-registry data.BMC emergency medicine · 2025Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
backgroundThe National Early Warning Score 2 (NEWS2) has been adopted as the standard approach for early detection of deterioration in clinical settings in the UK, and is also used in many non-UK settings. Limitations have been identified, including a reliance on 'normal' physiological parameters without accounting for individual variation.
objectiveThis review aimed to map how the NEWS2 has been modified to improve its predictive accuracy while placing minimal additional burden on clinical teams.
methodsThe Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA-ScR) and the Population, Intervention, Comparator, Outcome, and Study (PICOS) frameworks were followed to structure the review. Six databases (CINAHL, PubMed, Embase, ScienceDirect, Cochrane Library and Web of Science) were searched for studies which reported the predictive accuracy of a modified version of NEWS2. The references were screened based on keywords using EndNote 21. Title, abstract and full-text screening were performed by 2 reviewers independently in Rayyan. Data was extracted into a pre-established form and synthesised in a descriptive analysis.
resultsTwelve studies were included from 12,867 references. In 11 cases, modified versions of NEWS2 demonstrated higher predictive accuracy for at least one outcome. Modifications that incorporated demographic variables, trend data and adjustments to the weighting of the score's components were found to be particularly conducive to enhancing the predictive accuracy of NEWS2.
conclusionsThree key modifications to NEWS2-incorporating age, nuanced treatment of FiO
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Registered trials
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