Evidence map›Paper›PMID 40069620›Full record

ArticleBMC pregnancy and childbirth2025

Analysis of the uterine rupture during pregnancy and delivery in a provincial maternal and children care hospital in China: 2013-2022.

Bin Wen, Guihua Ding, Chuan Xiao, Yaru Chen, Fanjuan Kong

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Article in BMC pregnancy and childbirth, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

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5citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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5 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Bin WenPatient Case Management Section, Hunan Provincial Maternal and Child Health Care Hospital, Changsha, Hunan Province, China.
Guihua DingPatient Case Management Section, Hunan Provincial Maternal and Child Health Care Hospital, Changsha, Hunan Province, China.
Chuan XiaoPatient Case Management Section, Hunan Provincial Maternal and Child Health Care Hospital, Changsha, Hunan Province, China.
Yaru ChenPatient Case Management Section, Hunan Provincial Maternal and Child Health Care Hospital, Changsha, Hunan Province, China.
Fanjuan KongPatient Case Management Section, Hunan Provincial Maternal and Child Health Care Hospital, Changsha, Hunan Province, China. kfj8541684@163.com.

Funding

the Hunan Provincial Health and Wellness Commission 202112030366
6 · The paper itself

Abstract

backgroundUterine rupture is rare and life-threatening for both mothers and newborns. This study aimed to explore the clinical manifestation, site of rupture, obstetric risk factors, maternal and neonatal complications, and birth outcomes with mid-trimester and late-pregnancy uterine rupture.

methodsData from patients with uterine rupture occurring at Hunan Maternal and Child Health Hospital between January 2013 and December 2022 were reviewed retrospectively.

results153,722 deliveries occurred during the 10 years of the study period. A total number of 129 uterine ruptures were identified: 12 ruptures occurred in the second trimester and 117 cases of uterine rupture diagnosed at or after 28 weeks gestation. The total incidence was 8.4/10,000. Most of the patients had a history of cesarean section (73.6%). 59.7% cases had a history of dilation and curettage. The rupture was more likely to occur on the lower uterine segment (86.82%). Seventy-one patients (55%) presented with abdominal pain or vaginal bleeding. Twenty-seven (20.9%) cases underwent a labor trial. There were 17 perinatal deaths associated with uterine rupture and neonatal asphyxia was observed in five infants. There was one maternal death. Postpartum hemorrhage occurred in 25 cases. Five patients underwent hysterectomy. Patients with uterine rupture during mid-trimester were more likely to receive a blood transfusion and exhibited higher rates of bladder injury.

conclusionUterine rupture especially mid-gestational uterine rupture is rare and remains a diagnostic challenge. Remarkably worse maternal outcomes were seen in patients with second-trimester rupture when compared with patients who experienced late-pregnancy rupture. Pregnant women with a history of uterine surgery, even at an early gestational age, should be closely monitored by obstetricians for the risk of uterine rupture if they experience persistent abdominal pain. Early recognition and prompt intervention are key to improve maternal and child outcomes.

Indexed as

Delivery, ObstetricUterine RuptureAdultCesarean SectionChinaFemaleHumansHysterectomyIncidenceInfant, NewbornPostpartum HemorrhagePregnancyPregnancy OutcomePregnancy Trimester, SecondRetrospective StudiesRisk FactorsCaesarean sectionMid-trimesterUterine rupture

Identifiers

PMID40069620
PMCPMC11899631

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.