ArticleBMC genomics2025
Transcriptional profiles reveal physiological mechanisms for compensation during a simulated marine heatwave in Yellowtail Kingfish (Seriola lalandi).
Article in BMC genomics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Liver Antioxidant, Transcriptomic and Metabolomic Responses to Heatwaves in an Aquatic Turtle Species,Animals : an open access journal from MDPI · 2026Article
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Authors and funding
7 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundChanging ocean temperatures are already causing declines in populations of marine organisms. Predicting the capacity of organisms to adjust to the pressures posed by climate change is a topic of much current research effort, particularly for species we farm or harvest. To explore one measure of phenotypic plasticity, the physiological compensations in response to heat stress as might be experienced in a marine heatwave, we exposed Yellowtail Kingfish (Seriola lalandi) to sublethal heat stress, and used the transcriptome in gill and muscle, benchmarked against heat shock proteins and oxidative stress indicators, to characterise the acute heat stress response (6 h after the initiation of stress), and the physiological compensation to that response (24 and 72 h after the initiation of stress).
resultsThe heat stress experiments induced elevations in heat shock proteins, as measured in blood, demonstrating the sublethal stress level. The initial response (6 h) to heat stress included the expected cellular stress response. Exposure of 24 h or more led to altered transcriptomic patterns for protein degradation, membrane transporters, and primary metabolism. In the muscle, numerous transcripts with mitochondrial function had altered abundance. There was a profound change to the regulation of transcription, as well as numerous transcripts with differential exon usage, suggesting that this may be a mechanism for conferring physiological resilience to heat stress.
conclusionsThese results demonstrate the processes involved in acclimation to heat stress in this species, and the utility of using the transcriptome to assess plasticity. It also showed that differential exon usage may be an important mechanism for conferring plasticity. Future work should investigate the role of genome regulation, and alternative splicing in particular, on conferring resilience to temperature changes.
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