ArticleScientific reports2025
Association of whole blood heavy metal concentrations with kidney function.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed.
- Toenail metal concentrations and kidney health among young people at risk of chronic kidney disease of uncertain etiology.Environmental epidemiology (Philadelphia, Pa.) · 2026Article
- Proximal Tubule Reabsorption and CKD Progression in the General Population.Kidney international reports · 2026Article
- Associations of plasma concentrations of heavy metals and trace elements with estimated glomerular filtration rate and chronic kidney disease: a population-based study.Clinical kidney journal · 2026Article
- Distribution of Toxic and Essential Elements in Autopsy Organs of Subjects Living in South-Eastern Poland.International journal of molecular sciences · 2026Article
- Environmental Exposure to Cadmium and Lead Exacerbates Kidney Function in People with Diabetes.Journal of xenobiotics · 2025Article
- Longitudinal associations and interactions of heat and metal(loid) exposure with kidney outcomes in Mexican agricultural workers.Environmental research · 2025Article
- Trace Elements in Post-Mortem Tissues: A Review of Current Evidence and Forensic Challenges.Toxics · 2025Review
- Impact of Heavy Metals on the Antioxidant Activity of Vitamin D: A Metabolic Perspective.Metabolites · 2025Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Relatively elevated concentrations of arsenic, lead, and mercury are toxic to the kidneys. However, it is unknown whether kidney function is influenced by these metals in the general population without kidney diseases and without known exposure to these metals. We did a retrospective analysis of data collected from 58,864 outpatients in Germany from January 2014 to October 2022 undergoing measurements of arsenic, lead, and mercury. Routine clinical laboratory parameters were entered into the database if they were analyzed in the same patient within +/- four weeks of the metal analysis. The estimated glomerular filter rate (eGFR) was calculated using the 2021 CKD-EPI equation. The mean age of the study participants was 50.3 ± 17.1, of which 61.8% were women. Complete blood count, CRP, fasting glucose, liver and lipid values, and thyroid function parameters were within the normal range. Median (IQR) eGFR level was 92.14 (79.44-103.85) mL/min/1.73m
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