Evidence map›Paper›PMID 40069380›Full record

ArticleScientific reports2025

Examining the effects of extremely low-frequency magnetic fields on cognitive functions and functional brain markers in aged mice.

Senka Hadzibegovic, Olivier Nicole, Vojislav Andelkovic, Florence Poulletier de Gannes, Annabelle Hurtier, Isabelle Lagroye, Bruno Bontempi

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. [Effect of 40 Hz pulsed magnetic field on mitochondrial dynamics and heart rate variability in dementia mice].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Senka Hadzibegovic *Neurocentre Magendie, INSERM U1215, Université de Bordeaux, 33000, Bordeaux, France. senka.hadzibegovic@u-bordeaux.fr.
Olivier Nicole *Institut Interdisciplinaire de Neurosciences, CNRS UMR 5297, Université de Bordeaux, 33000, Bordeaux, France.
Vojislav AndelkovicLaboratoire de l'Intégration du Matériau au Système, CNRS UMR 5218, Université de Bordeaux, 33405, Talence, France and Ecole Pratique des Hautes Etudes-PSL, 75014, Paris, France.
Florence Poulletier de GannesLaboratoire de l'Intégration du Matériau au Système, CNRS UMR 5218, Université de Bordeaux, 33405, Talence, France and Ecole Pratique des Hautes Etudes-PSL, 75014, Paris, France.
Annabelle HurtierLaboratoire de l'Intégration du Matériau au Système, CNRS UMR 5218, Université de Bordeaux, 33405, Talence, France and Ecole Pratique des Hautes Etudes-PSL, 75014, Paris, France.
Isabelle LagroyeLaboratoire de l'Intégration du Matériau au Système, CNRS UMR 5218, Université de Bordeaux, 33405, Talence, France and Ecole Pratique des Hautes Etudes-PSL, 75014, Paris, France.
Bruno BontempiInstitut de Neurosciences Cognitives et Intégratives d'Aquitaine, CNRS UMR 5287, Université de Bordeaux and Ecole Pratique des Hautes Etudes, 33000, Bordeaux, France. bruno.bontempi@u-bordeaux.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extremely low-frequency magnetic fields (ELF-MFs) are ubiquitously present in various environments of everyday life. While surveys from the World Health Organization (WHO) have not demonstrated the existence of ELF-MF-induced harmful consequences in healthy subjects, whether older adults are more vulnerable to the effects of residential and occupational ELF-MF exposure, and therefore may be at risk, remains unsettled. Here, we explored this potential health issue by investigating, in aged mice, the effects of chronic exposure to ELF-MFs (50 Hz ELF-MF at 1 mT for 8 h/day, 5 days/week for 12 consecutive weeks) on cognitive functions and expression profile of brain markers typically associated with aggravated aging or the development of Alzheimer`s disease (AD). Sham-exposed mice showed a significant age-related decline in spatial memory functions compared to young adult mice. However, this expected pattern was neither exacerbated nor counteracted by chronic exposure to ELF-MFs. No difference in hippocampal expression of APP-695, Aβ

Indexed as

AgingBrainCognitionMagnetic FieldsAlzheimer DiseaseAmyloid beta-PeptidesAnimalsBiomarkersGlial Fibrillary Acidic ProteinHippocampusMaleMiceMice, Inbred C57BLPeptide FragmentsS100 Calcium Binding Protein beta SubunitSpatial MemoryAmyloid beta-PeptidesBiomarkersGlial Fibrillary Acidic ProteinPeptide FragmentsS100 Calcium Binding Protein beta Subunittau ProteinsAgingAlzheimer’s diseaseExtremely low-frequency magnetic fieldsMemory functions

Identifiers

PMID40069380
PMCPMC11897315

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.