ArticleScientific reports2025
Risk factors and protective strategies for hypotony following preserflo microshunt implantation.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Bleb-related infection associated with an intraluminal stent suture after PreserFlo MicroShunt implantation: a case report.American journal of ophthalmology case reports · 2026Article
- Factors Associated with Favorable One-Year Outcomes After PreserFlo MicroShunt Implantation: Insights from Anterior Segment Optical Coherence Tomography.Advances in therapy · 2026Article
- Comparison of one-year postoperative outcomes between PreserFlo MicroShunt and trabeculectomy in Japanese patients with open angle glaucoma: a retrospective cohort study using propensity score matching.Japanese journal of ophthalmology · 2026Observational
- Incidence and clinical features of malignant glaucoma after Preserflo MicroShunt implantation.Japanese journal of ophthalmology · 2026Article
- A-stream glaucoma shunt versus trabeculectomy: 1-year results on efficacy and safety.Scientific reports · 2026Article
- Outcomes of Ab Interno 63 µm vs. 45 µm XENJournal of clinical medicine · 2026Article
- The JFC Method: A Proof-of-Concept Report on the Surgical Technique and Initial Feasibility of a Novel Flanged-Cord Temporary Occlusion for Non-Valved Glaucoma Drainage Devices.Clinical ophthalmology (Auckland, N.Z.) · 2026Article
- Article
- 3-year real-world outcomes of standalone PreserFlo MicroShunt implantation - effectiveness and safety profile.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025Article
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7 authors.
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Abstract
The PreserFlo MicroShunt (PMS) is a minimally invasive surgical device for glaucoma management. However, postoperative hypotony remains a significant complication. This retrospective cohort study analyzed 471 eyes to evaluate the efficacy of PMS implantation in reducing intraocular pressure (IOP) and medication dependency, as well as to identify risk factors associated with hypotony. The median IOP decreased significantly from 19 mmHg preoperatively to 10 mmHg three months postoperatively, with the median medications score dropping to zero. Postoperative hypotony occurred in 18.7% of the cases. Multivariate analysis identified preoperative IOP ≥ 25 mmHg (odds ratio (OR): 2.01, 95% confidence interval (CI): 1.00-4.02, p = 0.049) and medication scores ≥ 5 (OR: 2.12, 95% CI: 1.13-3.96, p = 0.019) as significant risk factors for hypotony, while axial length ≥ 25.5 mm (OR: 0.19, 95% CI: 0.09-0.39, p < 0.001) and intraluminal suture stenting (OR: 0.08, 95% CI: 0.03-0.25, p < 0.001) were significantly protective. Importantly, intraluminal suture stenting mitigated the risk of hypotony without compromising the short-term surgical outcomes. These findings emphasize the need for careful patient selection and the potential of intraluminal suture stenting as an effective intraoperative strategy to improve the safety and outcomes of PMS implantation.
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