Evidence map›Paper›PMID 40069286›Full record

ArticleScientific reports2025

Role of aspartate 42 and histidine 79 in the aiPLA

Pushpa Kakchingtabam, Sharifun Shahnaj, Anju Kumari, Japani Longjam, A N Wungnaopam, Khundrakpam Herojit Singh, Nasir A Siddiqui, Rajendrakumar Singh Laishram, Aron B Fisher, Hamidur Rahaman

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Pushpa KakchingtabamDepartment of Biotechnology, Manipur University, Imphal, Manipur, 795003, India.
Sharifun ShahnajDepartment of Biotechnology, Manipur University, Imphal, Manipur, 795003, India.
Anju KumariDr. B. R. Ambedkar Center for Biomedical Research, University of Delhi, Delhi, 110007, India.
Japani LongjamDepartment of Biotechnology, Manipur University, Imphal, Manipur, 795003, India.
A N WungnaopamDepartment of Biotechnology, Manipur University, Imphal, Manipur, 795003, India.
Khundrakpam Herojit SinghDepartment of Biotechnology, Manipur University, Imphal, Manipur, 795003, India.
Nasir A SiddiquiDepartment of Pharmacognosy, College of Pharmacy, King Saud University, 11451, Riyadh, Saudi Arabia.
Rajendrakumar Singh LaishramDr. B. R. Ambedkar Center for Biomedical Research, University of Delhi, Delhi, 110007, India.
Aron B FisherInstitute for Environmental Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104-6068, USA.
Hamidur RahamanDepartment of Biotechnology, Manipur University, Imphal, Manipur, 795003, India. rahamanh@manipuruniv.ac.in.

Funding

UPTAKE AND REUTILIZATION OF SURFACTANT COMPONENTSP01HL019737 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI FISHER, ARON B. · 1985 to 2013
$23.6M
Role of Peroxiredoxin 6 in the Repair of Peroxidized Cell MembranesR01HL102016 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI FISHER, ARON B. · 2010 to 2018
$4.6M
Department of Biotechnology, Ministry of Science and Technology, India BT/359/NE/TBP/2012NHLBI NIH HHS P01 HL019737NHLBI NIH HHS R01 HL102016NIH HHS HL19737
6 · The paper itself

Abstract

Peroxiredoxin 6 (Prdx6), a unique non-seleno peroxidase, is a bifunctional protein with GSH peroxidase at pH 7.4 and calcium independent phospholipase A

Indexed as

Aspartic AcidHistidinePeroxiredoxin VIPhospholipases A2HumansHydrogen-Ion ConcentrationModels, MolecularMutagenesis, Site-DirectedMutationProtein MultimerizationAspartic AcidHistidinePeroxiredoxin VIPhospholipases A2PRDX6 protein, human1, 2,-bis palmitoyl-sn-glycero-3-phosphocholineCalcium independent phospholipase A2Circular dichroismPeroxiredoxin 6Thioredoxinπ glutathione S-transferase

Identifiers

PMID40069286
PMCPMC11897370

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.