Evidence map›Paper›PMID 40069253›Full record

ArticleScientific reports2025

Brain Perfusion, Atrophy, and Dopaminergic Changes in Amyloid Negative Logopenic Primary Progressive Aphasia.

Sungwoo Kang, Seun Jeon, Young-Gun Lee, Mijin Yun, HyangHee Kim, Byoung Seok Ye

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Considerations in Alzheimer's Disease in Women.Current neurology and neuroscience reports · 2026
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sungwoo Kang *Department of Neurology, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea.
Seun Jeon *Metabolism-Dementia Research Institute, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea.
Young-Gun LeeDepartment of Neurology, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, 10380, Republic of Korea.
Mijin YunDepartment of Nuclear Medicine, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea.
HyangHee KimGraduate Program in Speech-Language Pathology, Department and Research Institute of Rehabilitation Medicine, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea. hkim97.yonsei@gmail.com.
Byoung Seok YeDepartment of Neurology, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea. romel79@gmail.com.

Funding

Korea Health Industry Development Institute HR22C141101the Ministry of Science and ICT Project Number: 1711196790, RS-2023-00247272
6 · The paper itself

Abstract

Although most cases of logopenic variant primary progressive aphasia (lvPPA) are caused by Alzheimer's disease (AD), Lewy body disease (LBD) has also been reported. We assessed brain perfusion, atrophy, dopamine transporter (DAT) uptake, and language function among patients with lvPPA based on beta-amyloid. Thirty-three patients with lvPPA and 28 healthy controls (HCs) underwent MRI,

Indexed as

Aphasia, Primary ProgressiveBrainDopamineAgedAmyloid beta-PeptidesAtrophyCase-Control StudiesDopamine Plasma Membrane Transport ProteinsFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedPositron-Emission TomographyAmyloid beta-PeptidesDopamineDopamine Plasma Membrane Transport ProteinsAlzheimer’s diseaseLewy body diseaseLogopenic primary progressive aphasiaPositron emission tomography

Identifiers

PMID40069253
PMCPMC11897146

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.