Evidence map›Paper›PMID 40069194›Full record

ArticleScientific reports2025

Impaired myocardial deformation and aortic distensibility by cardiac MRI in girls with Turner syndrome.

Nihal M Batouty, Farah A Shokeir, Donia M Sobh, Basma Gadelhak, Wafaa Laimon, Nanees Abdelbadie Salem, Mohamed Abdelghafar Hussein, Ahmed M Tawfik

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Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nihal M BatoutyDepartment of Diagnostic and Interventional Radiology, Faculty of Medicine, Mansoura University, 12 El-Gomhoreya street, 35112, Mansoura, Egypt.
Farah A ShokeirDepartment of Diagnostic and Interventional Radiology, Faculty of Medicine, Mansoura University, 12 El-Gomhoreya street, 35112, Mansoura, Egypt.
Donia M SobhDepartment of Diagnostic and Interventional Radiology, Faculty of Medicine, Mansoura University, 12 El-Gomhoreya street, 35112, Mansoura, Egypt.
Basma GadelhakDepartment of Diagnostic and Interventional Radiology, Faculty of Medicine, Mansoura University, 12 El-Gomhoreya street, 35112, Mansoura, Egypt.
Wafaa LaimonPediatric Endocrinology and Diabetes Unit, Department of Pediatrics, Faculty of Medicine, Mansoura University Children Hospital, Mansoura University, Mansoura, Egypt.
Nanees Abdelbadie SalemPediatric Endocrinology and Diabetes Unit, Department of Pediatrics, Faculty of Medicine, Mansoura University Children Hospital, Mansoura University, Mansoura, Egypt.
Mohamed Abdelghafar HusseinPediatric department, Faculty of medicine Kafrelsheikh University, Kafrelsheikh, Egypt.
Ahmed M TawfikDepartment of Diagnostic and Interventional Radiology, Faculty of Medicine, Mansoura University, 12 El-Gomhoreya street, 35112, Mansoura, Egypt. ahm_m_tawfik@hotmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Girls and women with Turner syndrome (TS) suffer from increased risk of cardiovascular diseases. We hypothesized that left ventricular (LV) myocardial strain and aortic elasticity will be impaired in girls with TS. Cardiac MRI of 45 girls with TS and 14 healthy control girls was performed. Tissue tracking was used to assess LV Global Longitudinal (GLS), circumferential (GCS), radial short and long axes (GRS SAX and GRS LAX) in patients compared to controls. Maximal and minimal aortic areas were measured in ascending aorta, proximal descending, and aorta at diaphragm. Regional strain and distensibility were calculated using previously validated formulas. Comparisons were made between patients with and without bicuspid aortic valve (BAV). Inter-observer agreement was assessed for myocardial strain and aortic strain and distensibility. Results of the study showed GLS was significantly impaired in TS patients - 15.6 ± 1.8% compared to the control group - 17.2 ± 1%, p value = 0.013. No significant differences were observed in other strain parameters. Aortic diameter was similar in patients and control groups. Ascending aorta strain and distensibility were significantly lower in TS patients (33 ± 19% and 9.1 ± 5.5 mm Hg

Indexed as

AortaMagnetic Resonance ImagingMyocardiumTurner SyndromeAdolescentCase-Control StudiesChildFemaleHeart VentriclesHumansAortic distensibilityAortic strainCardiac MRIMyocardial strainTurner syndrome

Identifiers

PMID40069194
PMCPMC11897320

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