ArticleJournal of psychiatry & neuroscience : JPN
Abnormalities in large-scale brain network dynamics in late-life depression with suicidal ideation: an EEG microstate analysis.
Abstract read
In one paragraph
Article in Journal of psychiatry & neuroscience : JPN. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Gamma-band cortical functional network abnormalities in late-life depression with suicidal ideation: insights from EEG graph theory and machine learning.Journal of psychiatry & neuroscience : JPN · 2026Article
- Altered EEG microstate associated with anxiety and somatization symptoms in major depressive disorder.Frontiers in psychiatry · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Yicheng LinFrom The Geriatric Neuroscience Center, The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, China (Y. Lin, Wu, Zhang, G. Lin, Zeng, Lao, Zhou, Chen, Wang, Xu, Yang, Ning, Zhong); the First School of Clinical Medicine, Southern Medical University, Guangzhou, China (Ning); the Guangdong Engineering Technology Research Center for Translational Medicine of Mental Disorders, Guangzhou, China (Ning); the Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, China (Ning); the Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, China (Ning, Zhong).
Zhangying WuFrom The Geriatric Neuroscience Center, The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, China (Y. Lin, Wu, Zhang, G. Lin, Zeng, Lao, Zhou, Chen, Wang, Xu, Yang, Ning, Zhong); the First School of Clinical Medicine, Southern Medical University, Guangzhou, China (Ning); the Guangdong Engineering Technology Research Center for Translational Medicine of Mental Disorders, Guangzhou, China (Ning); the Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, China (Ning); the Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, China (Ning, Zhong).
Min ZhangFrom The Geriatric Neuroscience Center, The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, China (Y. Lin, Wu, Zhang, G. Lin, Zeng, Lao, Zhou, Chen, Wang, Xu, Yang, Ning, Zhong); the First School of Clinical Medicine, Southern Medical University, Guangzhou, China (Ning); the Guangdong Engineering Technology Research Center for Translational Medicine of Mental Disorders, Guangzhou, China (Ning); the Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, China (Ning); the Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, China (Ning, Zhong).
Gaohong LinFrom The Geriatric Neuroscience Center, The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, China (Y. Lin, Wu, Zhang, G. Lin, Zeng, Lao, Zhou, Chen, Wang, Xu, Yang, Ning, Zhong); the First School of Clinical Medicine, Southern Medical University, Guangzhou, China (Ning); the Guangdong Engineering Technology Research Center for Translational Medicine of Mental Disorders, Guangzhou, China (Ning); the Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, China (Ning); the Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, China (Ning, Zhong).
Yijie ZengFrom The Geriatric Neuroscience Center, The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, China (Y. Lin, Wu, Zhang, G. Lin, Zeng, Lao, Zhou, Chen, Wang, Xu, Yang, Ning, Zhong); the First School of Clinical Medicine, Southern Medical University, Guangzhou, China (Ning); the Guangdong Engineering Technology Research Center for Translational Medicine of Mental Disorders, Guangzhou, China (Ning); the Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, China (Ning); the Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, China (Ning, Zhong).
Jingyi LaoFrom The Geriatric Neuroscience Center, The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, China (Y. Lin, Wu, Zhang, G. Lin, Zeng, Lao, Zhou, Chen, Wang, Xu, Yang, Ning, Zhong); the First School of Clinical Medicine, Southern Medical University, Guangzhou, China (Ning); the Guangdong Engineering Technology Research Center for Translational Medicine of Mental Disorders, Guangzhou, China (Ning); the Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, China (Ning); the Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, China (Ning, Zhong).
Huarong ZhouFrom The Geriatric Neuroscience Center, The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, China (Y. Lin, Wu, Zhang, G. Lin, Zeng, Lao, Zhou, Chen, Wang, Xu, Yang, Ning, Zhong); the First School of Clinical Medicine, Southern Medical University, Guangzhou, China (Ning); the Guangdong Engineering Technology Research Center for Translational Medicine of Mental Disorders, Guangzhou, China (Ning); the Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, China (Ning); the Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, China (Ning, Zhong).
Ben ChenFrom The Geriatric Neuroscience Center, The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, China (Y. Lin, Wu, Zhang, G. Lin, Zeng, Lao, Zhou, Chen, Wang, Xu, Yang, Ning, Zhong); the First School of Clinical Medicine, Southern Medical University, Guangzhou, China (Ning); the Guangdong Engineering Technology Research Center for Translational Medicine of Mental Disorders, Guangzhou, China (Ning); the Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, China (Ning); the Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, China (Ning, Zhong).
Qiang WangFrom The Geriatric Neuroscience Center, The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, China (Y. Lin, Wu, Zhang, G. Lin, Zeng, Lao, Zhou, Chen, Wang, Xu, Yang, Ning, Zhong); the First School of Clinical Medicine, Southern Medical University, Guangzhou, China (Ning); the Guangdong Engineering Technology Research Center for Translational Medicine of Mental Disorders, Guangzhou, China (Ning); the Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, China (Ning); the Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, China (Ning, Zhong).
Danyan XuFrom The Geriatric Neuroscience Center, The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, China (Y. Lin, Wu, Zhang, G. Lin, Zeng, Lao, Zhou, Chen, Wang, Xu, Yang, Ning, Zhong); the First School of Clinical Medicine, Southern Medical University, Guangzhou, China (Ning); the Guangdong Engineering Technology Research Center for Translational Medicine of Mental Disorders, Guangzhou, China (Ning); the Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, China (Ning); the Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, China (Ning, Zhong).
Mingfeng YangFrom The Geriatric Neuroscience Center, The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, China (Y. Lin, Wu, Zhang, G. Lin, Zeng, Lao, Zhou, Chen, Wang, Xu, Yang, Ning, Zhong); the First School of Clinical Medicine, Southern Medical University, Guangzhou, China (Ning); the Guangdong Engineering Technology Research Center for Translational Medicine of Mental Disorders, Guangzhou, China (Ning); the Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, China (Ning); the Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, China (Ning, Zhong).
Yuping NingFrom The Geriatric Neuroscience Center, The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, China (Y. Lin, Wu, Zhang, G. Lin, Zeng, Lao, Zhou, Chen, Wang, Xu, Yang, Ning, Zhong); the First School of Clinical Medicine, Southern Medical University, Guangzhou, China (Ning); the Guangdong Engineering Technology Research Center for Translational Medicine of Mental Disorders, Guangzhou, China (Ning); the Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, China (Ning); the Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, China (Ning, Zhong) ningjeny@126.com lovlaugh@163.com.
Xiaomei ZhongFrom The Geriatric Neuroscience Center, The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, China (Y. Lin, Wu, Zhang, G. Lin, Zeng, Lao, Zhou, Chen, Wang, Xu, Yang, Ning, Zhong); the First School of Clinical Medicine, Southern Medical University, Guangzhou, China (Ning); the Guangdong Engineering Technology Research Center for Translational Medicine of Mental Disorders, Guangzhou, China (Ning); the Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, China (Ning); the Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, China (Ning, Zhong) ningjeny@126.com lovlaugh@163.com.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPatients with late-life depression (LLD) with suicidal ideation (SI) often have more explicit suicide plans, and suicide attempts among older adults are more highly lethal than in other age groups. Increasing evidence suggests that people with SI in depression exhibit abnormal brain network connectivity; however, the relationship between suicidal ideation in LLD and brain network dynamics is still unclear.
methodsWe recruited patients with LLD and SI (LLD-SI), patients with LLD without SI (LLD-NSI), and age-matched healthy older adults. We collected 64-channel resting state electroencephalography (EEG) recordings of all participants and used microstate analysis to explore large-scale brain network dynamics.
resultsWe included 33 patients with LLD-SI, 29 patients with LLD-NSI, and 31 controls. We observed abnormal microstate parameters in the LLD-SI group, characterized by higher duration ( LIMITATIONS: The sample size was relatively small, the cross-sectional nature of this study prohibited exploring the causal relationship between abnormal microstate dynamics and suicidal ideation, and we did not include medication-naive patients with first-episode LLD.
conclusionThe study reveals altered microstate dynamics among patients with LLD-SI, compared with patients with LLD-NSI and controls. Our findings suggest that microstate dynamics could serve as potential neurobiomarkers for identifying SI in LLD.
Indexed as
BrainDepressionMajor Depressive DisorderNerve NetSuicidal IdeationAgedElectroencephalographyFemaleHumansMaleMiddle Aged
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.