Evidence map›Paper›PMID 40068220›Full record

ArticleThe American journal of tropical medicine and hygiene2025

Electronic Clinical Decision Support Tools to Manage Patients with Lower Respiratory Tract Infection: Clinicians' Perspectives in Sri Lanka.

Warsha De Zoysa, Dhammika Palangasinghe, Champica Bodinayake, Ajith Nagahawatte, Jayani Gamage, Maria D Iglesias-Ussel, Stefany Olague, Christina Galdieri, Ruvini Kurukulasooriya, Senali Weerasinghe and 10 more

Abstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Warsha De ZoysaDepartment of Medicine, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.
Dhammika PalangasingheDepartment of Medicine, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.
Champica BodinayakeDepartment of Medicine, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.
Ajith NagahawatteDuke-Ruhuna Collaborative Research Centre, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.
Jayani GamageDuke-Ruhuna Collaborative Research Centre, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.
Maria D Iglesias-UsselDepartment of Medicine, School of Medicine, Duke University, Durham, North Carolina.
Stefany OlagueDuke Clinical Research Institute, Duke University, Durham, North Carolina.
Christina GaldieriDuke Clinical Research Institute, Duke University, Durham, North Carolina.
Ruvini KurukulasooriyaDuke-Ruhuna Collaborative Research Centre, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.
Senali WeerasingheDuke-Ruhuna Collaborative Research Centre, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.
Madureka PremamaliDuke-Ruhuna Collaborative Research Centre, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.
James NgochoKilimanjaro Christian Medical Centre, Moshi, Tanzania.
Armstrong ObaleDuke-Ruhuna Collaborative Research Centre, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.
Hrishikesh ChakrabortyDepartment of Medicine, School of Medicine, Duke University, Durham, North Carolina.
Truls OstbyeDepartment of Family Medicine, Duke University, Durham, North Carolina.
Susanna NaggieDepartment of Medicine, School of Medicine, Duke University, Durham, North Carolina.
Christopher W WoodsDuke Global Health Institute, Duke University, Durham, North Carolina.
Evan MyersDepartment of Medicine, School of Medicine, Duke University, Durham, North Carolina.
Melissa H WattDepartment of Population Health Sciences, School of Medicine, University of Utah, Salt Lake City, Utah.
L Gayani TillekeratneDepartment of Medicine, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.

Funding

A randomized controlled trial of a novel, evidence-based algorithm for managing lower respiratory tract infection in a resource-limited settingR01AI168420 · NIAID · DUKE UNIVERSITY · PI GAYANI TILLEKERATNE · 2022 to 2026
$3.4M
NIAID NIH HHS R01 AI168420
6 · The paper itself

Abstract

In low-resource settings, providers often manage lower respiratory tract infections (LRTIs) without diagnostic tests, which may cause antibacterial overuse. Electronic clinical decision support tools (eCDSTs) can support evidence-based decision-making and judicious use of antibacterials. This study aimed to explore the potential of an eCDST to help providers in Sri Lanka effectively manage LRTI. Semi-structured interviews were conducted with 15 clinicians, including 10 males and five females, with an average of 11.6 years (range: 4-25 years) of clinical practice. The interview guide covered clinicians' interest in an eCDST to manage LRTI and their feedback regarding the desired features of such a tool. Interviews were audio-recorded, transcribed, and coded for themes related to: interest in an eCDST for LRTI, desired tool capabilities, development concerns, and tool design characteristics. All expressed interest in incorporating eCDSTs into their practice. However, the majority emphasized that clinical judgment must supersede recommendations from an eCDST. Four themes emerged regarding desired tool capabilities: information about the pathogen, treatment recommendations, severity of the LRTI, and monitoring of patient progress. Six themes emerged regarding tool development considerations: validated algorithms, regional specificity, seasonality, inclusion of patient's risk factors, scalability, and the importance of updated and locally relevant recommendations. Participants stressed that the tool design should be simple, timesaving, and internet-independent. Electronic clinical decision support tools are capable of improving patient care and reduce antibiotic overuse, which may impact downstream antibacterial resistance. Future research should develop an eCDST for LRTI with local input and evaluate its impact on appropriate antibacterial use and patient outcomes.

Indexed as

Anti-Bacterial AgentsDecision Support Systems, ClinicalRespiratory Tract InfectionsAdultClinical Decision-MakingFemaleHumansMaleMiddle AgedSri LankaAnti-Bacterial Agents

Identifiers

PMID40068220
PMCPMC12062695

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.