ArticleAnnals of the American Thoracic Society2025
Longitudinal Outcomes in Pi*MZ Alpha-1 Antitrypsin-Deficient Individuals with Tobacco Smoking History from the SPIROMICS Cohort.
Abstract read
In one paragraph
Article in Annals of the American Thoracic Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Longitudinal Outcomes of Pi*MZ versus Pi*MM Subjects Stratified by Former and Current Smoking Status.Annals of the American Thoracic Society · 2025Article
- Reply to AbushanabAnnals of the American Thoracic Society · 2025Article
- Matrix metalloproteinases and disease severity among PI*MZ and PI*ZZ individuals in the Genomic Research in Alpha-1 Antitrypsin Deficiency and Sarcoidosis (GRADS) cohort.BMJ open respiratory research · 2025Article
- Increased exacerbations and hospitalizations among PI*MZ compared to PI*MM individuals: an electronic health record analysis.Respiratory research · 2025Article
- Further Insights into Emphysema Progression and Lung Function Decline in MZ Alpha-1 Antitrypsin Deficiency.Annals of the American Thoracic Society · 2025Article
Corrections and comments
- Commented on by
Authors and funding
28 authors.
Igor BarjaktarevicDivision of Pulmonary, Critical Care, and Sleep Medicine and.ORCID 0000-0002-8096-0858
Roxana HixsonDivision of Pulmonary, Critical Care, and Sleep Medicine and.
Zian ZhuangDepartment of Biostatistics and.ORCID 0000-0002-6332-194X
Russell G BuhrDivision of Pulmonary, Critical Care, and Sleep Medicine and.ORCID 0000-0001-6159-7435
Vickram TejwaniDivision of Pumonary Medicine, Department of Pulmonary Medicine and.ORCID 0000-0003-2100-6148
R Graham BarrDepartment of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York.
Lori A BatemanCollaborative Studies Coordinating Center, Department of Biostatistics, Gillings School of Global Public Health, and.
Surya P BhattDivision of Pulmonary, Allergy, and Critical Care Medicine, University of Alabama at Birmingham, Birmingham, Alabama.ORCID 0000-0002-8418-4497
Eugene R BleeckerDivision of Pulmonary Medicine, Mayo Clinic, Phoenix, Arizona.
Christopher B CooperDivision of Pulmonary, Critical Care, and Sleep Medicine and.
Jeffrey L CurtisMedical Service, Ann Arbor Veterans Affairs Healthcare System, Ann Arbor, Michigan.
M Bradley DrummondDivision of Pulmonary Diseases and Critical Care Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.ORCID 0000-0002-6968-4610
Spyridon FortisDivision of Pulmonary, Critical Care, and Occupational Medicine, Department of Internal Medicine, Roy J. and Lucille A. Carver College of Medicine.ORCID 0000-0001-7807-6740
Auyon J GhoshDivision of Pulmonary and Critical Care Medicine, SUNY Upstate Medical University, Syracuse, New York.
MeiLan HanDivision of Pulmonary and Critical Care Medicine, University of Michigan, Ann Arbor, Michigan.
Nadia N HanselDivision of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Boston, Massachusetts.
Eric A HoffmanDepartment of Radiology.ORCID 0000-0001-8456-9437
Jill OharDivision of Pulmonary, Critical Care, Allergy, and Immunology, Wake Forest School of Medicine, Winston Salem, North Carolina.
Fernando J MartinezDivision of Pulmonary and Critical Care Medicine, UMass Chan Medical School, Worcester, Massachusetts.
Deborah A MeyersDivision of Pulmonary Medicine, Mayo Clinic, Phoenix, Arizona.
Robert PaineDivision of Respiratory, Critical Care, and Occupational Pulmonary Medicine, University of Utah, Salt Lake City, Utah.
Cheryl S PirozziDivision of Respiratory, Critical Care, and Occupational Pulmonary Medicine, University of Utah, Salt Lake City, Utah.
Robert SandhausDivision of Pulmonary and Critical Care Medicine, National Jewish Health, Denver, Colorado.
Charlie StrangeDivision of Pulmonary, Critical Care, Allergy, and Sleep Medicine, Medical University of South Carolina, Charleston, South Carolina; and.
Donald P TashkinDivision of Pulmonary, Critical Care, and Sleep Medicine and.
J Michael WellsDivision of Pulmonary, Allergy, and Critical Care Medicine, University of Alabama at Birmingham, Birmingham, Alabama.ORCID 0000-0001-9612-5454
Prescott WoodruffDivision of Pulmonary, Critical Care, Allergy, and Sleep Medicine, University of California San Francisco, San Francisco, California.
Victor E OrtegaDivision of Pulmonary Medicine, Mayo Clinic, Phoenix, Arizona.
Funding
Pulmonary Toxicology Facility CoreP30ES005605 · NIEHS · UNIVERSITY OF IOWA · PI Brandi Janssen · 1990 to 2026
$40.5MEffects of Rare Variants and Ancestry on Beta Agonist Response in Asthma and COPDR01HL142992 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ORTEGA, VICTOR E. · 2019 to 2023
$3.7MNHLBI NIH HHS L30 HL134025NHLBI NIH HHS R01 HL142992NIEHS NIH HHS P30 ES005605
Abstract
PubMed holds no abstract for this paper.
Indexed as
alpha 1-Antitrypsinalpha 1-Antitrypsin DeficiencyLungPulmonary Disease, Chronic ObstructivePulmonary EmphysemaSmokingTobacco SmokingAdultAgedDisease ProgressionFemaleForced Expiratory VolumeGenotypeHumansLongitudinal StudiesMalealpha 1-Antitrypsinalpha-1 antitrypsin deficiencyemphysemalung function declinePi*MZ heterozygositySERPINA-1
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.