Evidence map›Paper›PMID 40067782›Full record

ArticleJournal of acquired immune deficiency syndromes (1999)2025

Brief Report: Potential Gains in PrEP Coverage and Effect on Racial Disparities After Introduction of On-Demand and Long-Acting Injectable PrEP: Preferences of Men Who Have Sex With Men in the United States, 2021-2022.

Jeb Jones, Aaron J Siegler, Jennifer L Glick, Iaah L Lucas, Patrick S Sullivan, Supriya Sarkar, Leigh Ragone, M Keith Rawlings, Vani Vannappagari, Travis Sanchez

Abstract read
In one paragraph

Article in Journal of acquired immune deficiency syndromes (1999), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jeb JonesDepartment of Epidemiology, Emory University, Atlanta, GA.ORCID 0000-0001-9165-1658
Aaron J SieglerDepartment of Epidemiology, Emory University, Atlanta, GA.
Jennifer L GlickDepartment of Community Health Science and Policy, Louisiana State University Health Science Center, New Orleans, LA; and.
Iaah L LucasDepartment of Epidemiology, Emory University, Atlanta, GA.
Patrick S SullivanDepartment of Epidemiology, Emory University, Atlanta, GA.
Supriya SarkarViiV Healthcare, Durham, NC.
Leigh RagoneViiV Healthcare, Durham, NC.
M Keith RawlingsViiV Healthcare, Durham, NC.
Vani VannappagariViiV Healthcare, Durham, NC.
Travis SanchezDepartment of Epidemiology, Emory University, Atlanta, GA.

Funding

Virology and Molecular Biomarkers CoreP30AI050409 · NIAID · EMORY UNIVERSITY · PI Ann M Chahroudi, Colleen F Kelley · 2002 to 2026
$74.0M
NIAID NIH HHS P30 AI050409
6 · The paper itself

Abstract

introductionThere are persistent race- and ethnicity-based disparities in HIV incidence among gay and bisexual men who have sex with men (GBMSM) in the United States, partially driven by inequities in distribution of pre-exposure prophylaxis (PrEP). We assessed how additional modalities of PrEP beyond daily oral might affect the uptake of PrEP and ongoing disparities in HIV incidence in the United States.

methodsIn an online survey of GBMSM in the United States, we presented participants with descriptions of each PrEP modality. Among GBMSM not willing to use daily oral PrEP, we assessed willingness to use on-demand or long-acting injectable (LA) PrEP. Among GBMSM using daily oral PrEP, we assessed willingness to switch to on-demand or LA PrEP.

resultsAmong GBMSM who were not willing to use daily oral PrEP, most were also not willing to use either on-demand or LA PrEP. In adjusted analyses, Hispanic/Latino, non-Hispanic/Latino Black, and non-Hispanic/Latino GBMSM of other races were more willing to use LA PrEP than non-Hispanic/Latino White GBMSM; none of the adjusted prevalence ratios was statistically significant. Most GBMSM currently taking daily oral PrEP reported a preference for staying on that regimen. Among those interested in switching, most were interested in on-demand PrEP.

conclusionsMost GBMSM not willing to use daily oral PrEP are also not willing to use other modalities of PrEP; most GBMSM who are currently using daily oral PrEP prefer to continue using that dosing strategy. Our results suggest that differential preferences in modalities of PrEP will not exacerbate existing disparities in PrEP distribution or HIV incidence.

Indexed as

Anti-HIV AgentsHealthcare DisparitiesHIV InfectionsHomosexuality, MalePre-Exposure ProphylaxisSexual and Gender MinoritiesAdultHumansInjectionsMaleMiddle AgedSurveys and QuestionnairesUnited StatesYoung AdultAnti-HIV Agents

Identifiers

PMID40067782
PMCPMC12403160

What OpenQuestion holds

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LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.