Evidence map›Paper›PMID 40067779›Full record

Observational studyClinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine2025

Phenotype of Achilles Tendon Ultrasonographic Abnormalities and Their Relationship to Future Time-Loss Injury.

Daniel M Cushman, Andrew S Nowak, W Reed Cone Le Beaumont, Derek Stokes

Abstract readObservational Study
In one paragraph

Observational study in Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

4 authors.

Daniel M CushmanDepartment of Physical Medicine & Rehabilitation, University of Utah, Salt Lake City, Utah.ORCID 0000-0002-4580-1173
Andrew S NowakDepartment of Physical Medicine and Rehabilitation, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania; and.
W Reed Cone Le BeaumontUniversity of Utah, Spencer Fox Eccles School of Medicine, Salt Lake City, Utah.
Derek StokesDepartment of Physical Medicine & Rehabilitation, University of Utah, Salt Lake City, Utah.

Funding

Utah Center for Clinical and Translational ScienceUL1TR002538 · NCATS · UNIVERSITY OF UTAH · PI HESS, RACHEL, MAJERSIK, JENNIFER JUHL · 2018 to 2022
$26.0M
CTSA UM1 Program at University of UtahUM1TR004409 · NCATS · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI RACHEL HESS, Jennifer Juhl Majersik · 2023 to 2026
$21.9M
NCATS NIH HHS UL1 TR002538NCATS NIH HHS UM1 TR004409PAC-12, National Center for Advancing Translational Sciences UL1TR002538
6 · The paper itself

Abstract

objectiveTo identify specific tendon morphologies on ultrasonography of the Achilles tendon (AT) that later develop time-loss injury.

designBlinded post hoc analysis of a 2-year prospective, observational study of 944 AT sonographic videos to identify morphologic characteristics of diagnosed Achilles tendinopathies associated with future time-loss injury. The second year was used to validate the findings from the first year.

settingN/A. PATIENTS/

participantsFour hundred seventy-three National Collegiate Athletic Association student-athletes from 3 institutions over 2 years of data collection (57.7% females; 20.1 ± 1.6 years of age; 23.1 ± 2.8 kg/m 2 of body mass index; 9.4 ± 3.6 years of sport experience). INTERVENTIONS/ASSESSMENT OF RISK FACTORS: Particular tendon morphologies were used to develop 3 ultrasonographic imaging rules that were used to predict AT injury leading to time loss in sport.

main outcome measuresPositive predictive value (PPV) and negative predictive values of particular tendon morphologies associated with the development of time-loss injury within 1 year.

resultsOne of 3 morphologies, a deep mid-substance focal hypoechogenic area, was validated on 2 separate data sets and found to have a 33.3% PPV in both years for the development of time-loss injury.

conclusionResults suggest a specific phenotype of sonographic abnormality of the AT that suggests a 1-in-3 chance of developing time-loss injury within a year. Detecting abnormality of future AT before symptoms develop may allow for rehabilitation strategies to prevent or reduce time-loss.

Indexed as

Achilles TendonAthletic InjuriesTendinopathyAdolescentFemaleHumansMalePhenotypePredictive Value of TestsProspective StudiesRisk FactorsUltrasonographyYoung Adult

Identifiers

PMID40067779
PMCPMC12535227

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.