Evidence map›Paper›PMID 40067619›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2025

Detection of Monocytic Myeloid-Derived Suppressor Cells in the Human Brain and Blood.

María Cristina Ortega, Virginia Vila-Del Sol, Isabel Machín-Díaz, Diego Clemente

Abstract read
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In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

María Cristina OrtegaNeuroimmune-Repair Group, Hospital Nacional de Parapléjicos-SESCAM-IDISCAM, Toledo, Spain.
Virginia Vila-Del SolFlow Cytometry Service, Hospital Nacional de Parapléjicos, SESCAM-IDISCAM, Toledo, Spain.
Isabel Machín-DíazNeuroimmune-Repair Group, Hospital Nacional de Parapléjicos-SESCAM-IDISCAM, Toledo, Spain.
Diego ClementeNeuroimmune-Repair Group, Hospital Nacional de Parapléjicos-SESCAM-IDISCAM, Toledo, Spain. dclemente@sescam.jccm.es.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The analysis of monocytic myeloid-derived suppressor cells (M-MDSCs) is gaining importance in the complex pathological context of neuroinflammatory diseases. M-MDSCs exert their potent immunoregulatory activity in both the central nervous system and the periphery. Since M-MDSCs lack a specific marker for their identification, the design and development of complex antibody panels for advanced confocal microscopy and flow cytometry techniques are needed to consistently and systematically detect them in both the brain and peripheral blood of human subjects.

Indexed as

BrainMonocytesMyeloid-Derived Suppressor CellsBiomarkersFlow CytometryHumansMicroscopy, ConfocalBiomarkersAntibody panelFlow cytometryHuman neuropathologyM-MDSCs

Identifiers

PMID40067619

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.