Evidence map›Paper›PMID 40067584›Full record

ReviewAdvances in experimental medicine and biology2025

The Ins and Outs of Thymic Epithelial Cell Differentiation and Function.

Minoru Matsumoto, Francisco Sobral, João S Cardoso, Takeshi Oya, Koichi Tsuneyama, Mitsuru Matsumoto, Nuno L Alves

Abstract readReview
PubMed Publisher
In one paragraph

Review in Advances in experimental medicine and biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Minoru MatsumotoDepartment of Molecular Pathology, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Francisco SobralInstituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal.
João S CardosoInstituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal.
Takeshi OyaDepartment of Molecular Pathology, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Koichi TsuneyamaDepartment of Pathology and Laboratory Medicine, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Mitsuru MatsumotoDivision of Molecular Immunology, Institute for Enzyme Research, Tokushima University, Tokushima, Japan. mitsuru@tokushima-u.ac.jp.
Nuno L AlvesInstituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal. nalves@i3s.up.pt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The thymus is an essential component of the immune system responsible for producing T cells. It is anatomically divided into two main regions: the outer cortex and the inner medulla. This chapter summarizes our current understanding of thymic stromal cell functions, with a particular focus on the interactions between these cells and T cells. This exploration aims to shed light on the pathogenesis of immune disorders, including autoimmunity.

Indexed as

Cell DifferentiationEpithelial CellsThymus GlandAnimalsAutoimmunityHumansStromal CellsT-Lymphocytes

Identifiers

PMID40067584

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.