Evidence map›Paper›PMID 40067561›Full record

ArticleInternational urology and nephrology2025

Injection of platelet-rich plasma combined with dexamethasone with visual internal urethrotomy in treating short bulbar urethral stricture.

Ahmed Mahmoud Reyad, Ahmed Mahmoud Mohammed, Tarek Ahmed Mahmoud, Ahmed Mahmoud Hasan, Atef Fathi, Ahmed Mamdouh Abd Elhamed

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Article in International urology and nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Ahmed Mahmoud ReyadUrology Department, Faculty of Medicine, Sohag University, University Street, Sohag City, 82515, Egypt. dr_ahmed_riyad@yahoo.com.ORCID http://orcid.org/0000-0002-9742-0065
Ahmed Mahmoud MohammedUrology Department, Faculty of Medicine, Sohag University, University Street, Sohag City, 82515, Egypt.
Tarek Ahmed MahmoudUrology Department, Faculty of Medicine, Sohag University, University Street, Sohag City, 82515, Egypt.
Ahmed Mahmoud HasanUrology Department, Faculty of Medicine, South Valley University, Qena, Egypt.
Atef FathiUrology Department, Faculty of Medicine, South Valley University, Qena, Egypt.
Ahmed Mamdouh Abd ElhamedUrology Department, Faculty of Medicine, Sohag University, University Street, Sohag City, 82515, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate long-term urethral patency of short bulbar urethral stricture management using visual internal urethrotomy with platelet-rich plasma (PRP) in conjunction with dexamethasone injection.

methodsThis retrospective study included 78 male patients with symptomatic short bulbar urethral stricture (diagnosed by ascending urethrography) who were treated by internal urethrotomy after injection of submucosal PRP combined with dexamethasone. Every patient was monitored for urethral stricture recurrence one month after catheter removal and twenty-four months after internal urethrotomy.

resultsThe etiology of urethral stricture was iatrogenic in 63 (80.8%) patients, inflammatory in 9 (11.5%) patients, and idiopathic in 6 (7.7%) patients. In terms of complications, two patients (2.7%) experienced bleeding per urethra, four patients (5.4%) had fever, three patients (4%) had hematuria, one patient (1.4%) had perineal abscess, and seven patients (9.5%) had a recurrence of stricture. The etiology of the stricture did not have any significance in patients who experienced recurrence (P = 0.77).

conclusionsOur findings suggest a potential protective effect of PRP and dexamethasone injection at the time of internal urethrotomy also decreased the length of stricture in case of recurrence. This protective effect lasted for at least 2 years.

Indexed as

DexamethasoneGlucocorticoidsPlatelet-Rich PlasmaUrethraUrethral StrictureAdultAgedCombined Modality TherapyHumansInjectionsMaleMiddle AgedRecurrenceRetrospective StudiesTreatment OutcomeDexamethasoneGlucocorticoidsDexamethasonePlatelet-rich plasmaUrethral strictureVisual internal urethrotomy

Identifiers

PMID40067561

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.