ArticleEuropean geriatric medicine2025
Frailty trajectories and mortality risk in community-dwelling older adults: a 9-year follow-up study.
Article in European geriatric medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Effect of bodyweight interval training on frailty status in older adults: a randomized controlled trial.European geriatric medicine · 2026Article
- Cognitive Impairment Predicts Adverse Outcomes in CKD.Kidney international reports · 2026Article
- Frailty Trajectories and Their Predictors in Chinese Empty-Nest Older Adults: An 8-Year Longitudinal Study.Healthcare (Basel, Switzerland) · 2026Article
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Authors and funding
8 authors.
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Abstract
purposeFrailty is a well-established risk factor for adverse health outcomes, yet its dynamic nature and predictors remain partially understood. This study aimed to investigate factors influencing frailty transitions and mortality risk among community-dwelling older adults.
methodsWe conducted a longitudinal study using a 9-year follow-up data from the Health, Well-being, and Aging Study (SABE, as known in Portuguese). A Markov model, fitted via multinomial logistic regression, identified factors independently associated with frailty transitions between waves. Four trajectory groups were identified: stable, worsening, improving, and fluctuating.
resultsA total of 1399 individuals aged 60 and older (61.8% female) were enrolled, with a mean age of 73.9 (SD ± 9.2) years. Among frailty transitions, 37.8% remained stable, 56.4% worsened, 1.3% improved, and 4.4% fluctuated. After adjusting for baseline variables, we found that older age, cognitive impairment, multimorbidity, and depressive symptoms were significantly linked to a higher risk of being frail at the next visit. The mortality risk was associated with male sex, older age, frailty, cognitive impairment, and multimorbidity.
conclusionSociodemographic and health-related factors contribute to increased risk of experiencing frailty and mortality among community-dwelling older adults. Further research is needed to identify modifiable factors influencing frailty transitions.
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