Evidence map›Paper›PMID 40067530›Full record

ArticleWorld journal of urology2025

Holmium: YAG laser enucleation of the prostate using the new cyber Ho generator with magneto technology: does it provide any advantages compared to thulium: YAG prostate enucleation?

Davide Perri, Umberto Besana, Federica Mazzoleni, Andrea Pacchetti, Tommaso Calcagnile, Matteo Maltagliati, Daniele Bianchi, Lorenzo Rivolta, Ilaria Ferrari, Flavio Mattuzzi and 2 more

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in World journal of urology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Observational
  3. Article
  4. Article
  5. Observational
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Davide PerriDivision of Urology, Azienda Socio Sanitaria Territoriale Lariana, Sant'Anna Hospital, Via Ravona 20 -San Fermo della Battaglia, 22042, Como, Italy. perri.davide90@gmail.com.
Umberto BesanaDivision of Urology, Azienda Socio Sanitaria Territoriale Lariana, Sant'Anna Hospital, Via Ravona 20 -San Fermo della Battaglia, 22042, Como, Italy.
Federica MazzoleniDivision of Urology, Azienda Socio Sanitaria Territoriale Lariana, Sant'Anna Hospital, Via Ravona 20 -San Fermo della Battaglia, 22042, Como, Italy.
Andrea PacchettiDivision of Urology, Azienda Socio Sanitaria Territoriale Lariana, Sant'Anna Hospital, Via Ravona 20 -San Fermo della Battaglia, 22042, Como, Italy.
Tommaso CalcagnileDivision of Urology, Azienda Socio Sanitaria Territoriale Lariana, Sant'Anna Hospital, Via Ravona 20 -San Fermo della Battaglia, 22042, Como, Italy.
Matteo MaltagliatiDivision of Urology, Azienda Socio Sanitaria Territoriale Lariana, Sant'Anna Hospital, Via Ravona 20 -San Fermo della Battaglia, 22042, Como, Italy.
Daniele BianchiDivision of Urology, Azienda Socio Sanitaria Territoriale Lariana, Sant'Anna Hospital, Via Ravona 20 -San Fermo della Battaglia, 22042, Como, Italy.
Lorenzo RivoltaDivision of Urology, Azienda Socio Sanitaria Territoriale Lariana, Sant'Anna Hospital, Via Ravona 20 -San Fermo della Battaglia, 22042, Como, Italy.
Ilaria FerrariDivision of Urology, Azienda Socio Sanitaria Territoriale Lariana, Sant'Anna Hospital, Via Ravona 20 -San Fermo della Battaglia, 22042, Como, Italy.
Flavio MattuzziDivision of Urology, Azienda Socio Sanitaria Territoriale Lariana, Sant'Anna Hospital, Via Ravona 20 -San Fermo della Battaglia, 22042, Como, Italy.
Eugenio VentimigliaDivision of Urology, IRCCS San Raffaele Hospital, University Vita-Salute San Raffaele, Milan, Italy.
Giorgio BozziniDivision of Urology, Azienda Socio Sanitaria Territoriale Lariana, Sant'Anna Hospital, Via Ravona 20 -San Fermo della Battaglia, 22042, Como, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess differences in efficacy and safety between Thulium:YAG laser enucleation of the prostate (ThuLEP) and enucleation performed with the Holmium:YAG Cyber Ho laser generator (HoLEP) with Magneto technology (Quanta System®).

methodsPatients with surgical indication for benign prostatic hyperplasia underwent ThuLEP using Cyber TM generator (Group A) versus HoLEP using Cyber Ho generator with Magneto technology (Group B). In Group A settings were 100W for enucleation and 35W for coagulation. In Group B early apical detachment and coagulation were performed with energy 1 J and frequency 30 Hz by applying Magneto technology. Enucleation was performed with energy 2 J and frequency 40 Hz by applying Virtual Basket pulse modulation.

results200 patients were enrolled (100 patients per group). Preoperative features were comparable. Mean prostate size was 78.9 vs. 80.5 ml in Group A vs. B (p = 0.09). Mean operative time was 70.6 vs. 64.3 min (p = 0.13) with mean enucleation time 48.8 vs. 43.7 min (p = 0.21) and morcellation time 21.2 vs. 14.6 min (p = 0.03) in ThuLEP vs. HoLEP group. Micturition improvements were comparable. Postoperative gross haematuria was significantly more frequent after ThuLEP and clots-induced urinary retention occurred in 5.0% of cases, compared to no cases after HoLEP (p = 0.02).

conclusionsHoLEP using the Cyber Ho generator with the application of Magneto technology for coagulation seems to provide an haemostatic advantage compared to ThuLEP, suggested by the significantly shorter morcellation time, higher morcellation efficiency and lower rate of postoperative gross haematuria and clots-induced urinary retention. Functional outcomes are comparable.

Indexed as

Lasers, Solid-StateLaser TherapyProstatectomyProstatic HyperplasiaThuliumAgedHumansMaleMiddle AgedTreatment OutcomeThuliumHoLEPMagneto technologyPeak powerProstate enucleationThuLEP

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.