Oxygen enhanced plasma discharge and its application as carrier gas for high-field asymmetric ion mobility spectroscopy.

Hua Li, Yuqiao Zhang, Xiaoxia Du, Wenxiang Xiao

Abstract read

In one paragraph

Article in Analytical and bioanalytical chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed

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3 · Its place in the literature

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1 citing paper in PubMed.

Interpol review of forensic drug chemistry, 2022-2025.Forensic science international. Synergy · 2026
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5 · Who and what money

Authors and funding

4 authors.

Hua LiSchool of Life and Environmental Sciences, Guilin University of Electronic Technology, Guilin, 541004, China. lihua@guet.edu.cn.

Yuqiao ZhangSchool of Life and Environmental Sciences, Guilin University of Electronic Technology, Guilin, 541004, China.

Xiaoxia DuSchool of Life and Environmental Sciences, Guilin University of Electronic Technology, Guilin, 541004, China. xiaoxia@guet.edu.cn.

Wenxiang XiaoSchool of Life and Environmental Sciences, Guilin University of Electronic Technology, Guilin, 541004, China. wenxiangxiao@126.com.

Funding

National Natural Science Foundation of China under Grant Numbers 62163009the Foundation of Guangxi Key Laboratory of Automatic Detecting Technology and Instruments (Guilin University of Electronic Technology) YQ23103the State key program of Guangxi Natural Science Foundation Program 2021JJD170019

6 · The paper itself

Abstract

This paper explores the application of a helium-oxygen mixture in gas curtain plasma ion source (GCP)-high-field asymmetric ion mobility spectroscopy (FAIMS). A gas mixture of oxygen and helium gases has been employed as the discharge gas. The experiments were conducted using 2-butanone, acetone, methanol, and ethanol as the sample under a radio frequency field strength of 20.3 kV/cm. When the flow rate of the discharge gas is fixed at 0.8 L/min and the helium oxygen mixture ratio is fixed at 7:1, the maximum ion signal can be obtained. With the flow rate of the carrier gas fixed at 1.2 L/min, using 100% oxygen as the carrier gas resulted in a 2.85-fold increase in signal intensity and a 72.67-fold improvement in resolution compared to a mixture of oxygen and nitrogen, as well as 100% nitrogen. Therefore, adding oxygen can not only improve the detection sensitivity of FAIMS, but also enhance its resolution.

Indexed as

Carrier gasGas curtain plasmaHigh-field asymmetric ion mobility spectroscopyOxygen

Identifiers

PMID40067472

DOI10.1007/s00216-025-05799-y

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.