ArticleBioprocess and biosystems engineering2025
A tandem conversion process for the synthesis of polyitaconic acid from glucose in the Aspergillus terreus culture.
Article in Bioprocess and biosystems engineering, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
In this study, a bio-based vinylidene monomer, itaconic acid (IA), produced by a fungus Aspergillus terreus NBRC 6123 was polymerized in the culture. The inhibition of IA polymerization by the culture components was eased by extraction with 4-methyltetrahydropyran (4mTHP). The extraction with 4mTHP for 4 days under aerobic condition resulted in IA production at 67.9 g/L (522 mM) in the organic phase from 180 g/L glucose. Interestingly, 4mTHP did not affect to the glucose consumption and respiration of A. terreus. IA polymerization in 4mTHP for 72 h using 400 mM IA and 1 mM 2,2'-azobis(4-methoxy-2,4-dimethylvaleronitrile) as a radical initiator under anaerobic condition by N
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