ArticleDevelopment (Cambridge, England)2025
Sex-biased gene expression precedes sexual dimorphism in the agonadal annelid Platynereis dumerilii.
Article in Development (Cambridge, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed.
- Faster and smaller: Heterochronic shift in gene expression leads to larval onset of spermatogenesis and miniaturized males.iScience · 2026Article
- Predetermined sex revealed by a female transient gut in non-feeding larvae of Osedax (Siboglinidae, Annelida).EvoDevo · 2025Article
- A genome resource for the marine annelid Platynereis spp.BMC genomics · 2025Article
- Sex-specific differential gene expression during stolonization in the branching syllid Ramisyllis kingghidorahi (Annelida, Syllidae).BMC genomics · 2025Article
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Abstract
Gametogenesis is the process by which germ cells differentiate into mature sperm and oocytes - cells that are essential for sexual reproduction. The sex-specific molecular programs that drive spermatogenesis and oogenesis can also serve as sex identification markers. Platynereis dumerilii is a research organism that has been studied in many areas of developmental biology. However, investigations often disregard sex, as P. dumerilii juveniles lack sexual dimorphism. The molecular mechanisms of gametogenesis in the segmented worm P. dumerilii are also largely unknown. In this study, we used RNA sequencing to investigate the transcriptomic profiles of gametogenesis in P. dumerilii juveniles. Our analysis revealed that sex-biased gene expression becomes increasingly pronounced during the advanced developmental stages, as worms approach maturation. We identified conserved genes associated with spermatogenesis, such as dmrt1, and with oogenesis, such as the previously unidentified gene psmt. Additionally, putative long non-coding RNAs were upregulated in both male and female gametogenic programs. This study provides a foundational resource for germ cell research in P. dumerilii and markers for sex identification, and offers comparative data to enhance our understanding of the evolution of gametogenesis mechanisms across species.
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