Evidence map›Paper›PMID 40067203›Full record

ArticleEpileptic disorders : international epilepsy journal with videotape2025

ILAE neuroimaging task force highlight: The utility of multimodal neuroimaging in diagnostic and presurgical workup of drug-resistant focal epilepsy.

Niccolò Biagioli, Maksim Parfyonov, Stefano Meletti, Giacomo Pavesi, John Archer, Boris C Bernhardt, Lorenzo Caciagli, Fernando Cendes, Yotin Chinvarun, Luis Concha and 9 more

Abstract readCase Reports
In one paragraph

Article in Epileptic disorders : international epilepsy journal with videotape, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Quantitative dual-tracerEuropean journal of nuclear medicine and molecular imaging · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Niccolò BiagioliNeurophysiology Unit and Epilepsy Centre, University of Modena and Reggio Emilia, Modena, Italy.
Maksim ParfyonovEpilepsy Center, Neurological Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Stefano MelettiNeurophysiology Unit and Epilepsy Centre, University of Modena and Reggio Emilia, Modena, Italy.
Giacomo PavesiNeurosurgery Unit, University of Modena and Reggio Emilia, Modena, Italy.
John ArcherDepartment Medicine, Austin Health, The University of Melbourne, Melbourne, Australia.
Boris C BernhardtMultimodal Imaging and Connectome Analysis Laboratory, McConnell Brain Imaging Centre, Montreal, Canada.
Lorenzo CaciagliDepartment of Neurology, Inselspital, Sleep-Wake-Epilepsy-Center, Bern University Hospital, University of Bern, Bern, Switzerland.
Fernando CendesDepartment of Neurology, University of Campinas - UNICAMP, Campinas, SP, Brazil.
Yotin ChinvarunEpilepsy Center, Neurology Unit, Phramongkutklao Hospital, Bangkok, Thailand.
Luis ConchaInstitute of Neurobiology, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Paolo FedericoHotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary, Canada.
William D GaillardCenter for Neuroscience, Children's National Hospital, George Washington University, Washington, DC, USA.
Eliane KobayashiDepartment of Neurology, Southwestern Peter O'Donnell Jr. Brain Institute, University of Texas, Dallas, Texas, USA.
Godwin OgboleDepartment of Radiology, University of Ibadan, Ibadan, Nigeria.
Stefan RamppDepartment of Neurosurgery and Department of Neuroradiology, University Hospital Erlangen, Erlangen, Germany.
Shuang WangDepartment of Neurology and Epilepsy Center, Zhejiang University, Hangzhou, China.
Gavin P WinstonDivision of Neurology, Department of Medicine, Queen's University, Kingston, Canada.
Irene WangEpilepsy Center, Neurological Institute, Cleveland Clinic, Cleveland, Ohio, USA.ORCID https://orcid.org/0000-0002-3829-5217
Anna Elisabetta VaudanoNeurophysiology Unit and Epilepsy Centre, University of Modena and Reggio Emilia, Modena, Italy.

Funding

MR Fingerprinting for EpilepsyR01NS109439 · NINDS · CLEVELAND CLINIC LERNER COM-CWRU · PI Dan Ma, Zhong Irene Wang · 2019 to 2026
$4.2M
NINDS NIH HHS R01 NS109439NINDS NIH HHS R01 NS109439Sao Paulo Research Foundation (FAPESP) Research Innovation and Dissemination Center 2013/07559-3
6 · The paper itself

Abstract

The ILAE Neuroimaging Task Force publishes educational case reports that highlight basic aspects of neuroimaging in epilepsy, consistent with ILAE's educational mission. In patients with drug-resistant focal epilepsy who are candidates for surgical intervention, the identification of structural abnormalities is a strong predictor of favorable postoperative seizure outcomes. When conventional imaging is insufficient, the integration of multimodal neuroimaging data with structural, metabolic, and functional imaging modalities is often helpful. The following two illustrative cases from two different centers highlight the challenges and needs to integrate the information from multiple imaging modalities for a more accurate diagnosis and resection planning of drug-resistant focal epilepsies. This approach can increase the number of patients eligible for surgery while minimizing the risk of postoperative deficits.

Indexed as

Drug Resistant EpilepsyEpilepsies, PartialMultimodal ImagingNeuroimagingAdultAdvisory CommitteesFemaleHumansMagnetic Resonance ImagingMaleMRI‐negativeMRI post‐processingmultimodalnonlesionalpresurgical evaluation

Identifiers

PMID40067203
PMCPMC12203302

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.