Evidence map›Paper›PMID 40067121›Full record

ReviewClinical pharmacology and therapeutics2025

Current Status and Future Directions in the Development of Digital Therapeutic Interventions for Neurodevelopmental Disorders.

Hyun-Ju Lee, Yoo Joo Jeong, Jun-Su Kim, Seung-Jae Kim, Unhui Jo, Su Jin Jun, Jongmin Lim, Jin-Yeop Park, Myungji Lee, Donggi Kim and 2 more

Abstract readReview
In one paragraph

Review in Clinical pharmacology and therapeutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Synergistic effects of Calebin A and docetaxel on apoptosis and migration in prostate cancer cells.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Hyun-Ju Lee *Department of Neural Development and Disease, Korea Brain Research Institute (KBRI), Daegu, Republic of Korea.ORCID 0000-0002-4532-6448
Yoo Joo Jeong *Department of Neural Development and Disease, Korea Brain Research Institute (KBRI), Daegu, Republic of Korea.ORCID 0009-0009-6598-3865
Jun-Su Kim *AI-Based Neurodevelopmental Diseases Digital Therapeutics Group, Korea Brain Research Institute (KBRI), Daegu, Republic of Korea.ORCID 0009-0001-1191-6079
Seung-Jae Kim *AI-Based Neurodevelopmental Diseases Digital Therapeutics Group, Korea Brain Research Institute (KBRI), Daegu, Republic of Korea.ORCID 0000-0001-9955-4254
Unhui Jo *AI-Based Neurodevelopmental Diseases Digital Therapeutics Group, Korea Brain Research Institute (KBRI), Daegu, Republic of Korea.ORCID 0000-0001-7309-4675
Su Jin JunAI-Based Neurodevelopmental Diseases Digital Therapeutics Group, Korea Brain Research Institute (KBRI), Daegu, Republic of Korea.ORCID 0009-0005-3617-0348
Jongmin LimAI-Based Neurodevelopmental Diseases Digital Therapeutics Group, Korea Brain Research Institute (KBRI), Daegu, Republic of Korea.ORCID 0009-0007-6106-6002
Jin-Yeop ParkAI-Based Neurodevelopmental Diseases Digital Therapeutics Group, Korea Brain Research Institute (KBRI), Daegu, Republic of Korea.ORCID 0009-0007-3448-3783
Myungji LeeAI-Based Neurodevelopmental Diseases Digital Therapeutics Group, Korea Brain Research Institute (KBRI), Daegu, Republic of Korea.ORCID 0009-0008-8700-9361
Donggi KimDigital Health Division, Daegu Digital Innovation Promotion Agency, Daegu, Republic of Korea.ORCID 0009-0007-1044-9249
Jeong-Heon SongAI-Based Neurodevelopmental Diseases Digital Therapeutics Group, Korea Brain Research Institute (KBRI), Daegu, Republic of Korea.ORCID 0009-0000-5443-1066
Hyang-Sook HoeDepartment of Neural Development and Disease, Korea Brain Research Institute (KBRI), Daegu, Republic of Korea.ORCID 0000-0001-8877-8594

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Innovations in digital technologies have emerged digital therapeutics (DTx) as a novel therapeutic intervention. DTx hold potential as novel theragnostics for disorders with broad diagnostic spectra, including neurodevelopmental diseases (NDDs). In this review, we highlight challenging factors in the successful development and deployment of DTx for NDDs with respect to patients, medical professionals, and manufacturers. We also discuss the implications of these factors and future directions for revitalizing DTx development for NDDs.

Indexed as

Digital TechnologyNeurodevelopmental DisordersHumansTelemedicine

Identifiers

PMID40067121
PMCPMC12087680

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.