Evidence map›Paper›PMID 40067034›Full record

ArticleAnesthesiology2025

Alluring Potential to Accelerate Emergence and Ameliorate Opioid-induced Respiratory Depression without Antagonizing Analgesia: Danavorexton Enters the Anesthetic Landscape.

Toshihiro Imamura, Max B Kelz

Abstract read
In one paragraph

Article in Anesthesiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Toshihiro ImamuraDepartment of Medicine, Division of Sleep Medicine, Department of Anesthesiology and Critical Care, Chronobiology and Sleep Institute, and Center for Neuroscience of Unconsciousness and Reanimation Research Alliance, University of Pennsylvania, Perelman School of Medicine, Philadelphia, Pennsylvania; Division of Pulmonary and Sleep Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Max B KelzDepartment of Anesthesiology and Critical Care, Chronobiology and Sleep Institute, Center for Neuroscience of Unconsciousness and Reanimation Research Alliance, and Mahoney Institute of Neuroscience University of Pennsylvania, Perelman School of Medicine, Philadelphia, Pennsylvania.ORCID 0000-0002-2803-6078

Funding

Brain Wide Anesthetic-Active Neuronal NetworkR01GM151556 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI Alexander Proekt · 2023 to 2026
$2.2M
Personalized Anesthetic Pharmacology Across the LifespanR01GM144377 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI KELZ, MAX · 2021 to 2024
$2.1M
Anesthesia and Sleep: Mechanisms of Generating Two Similar Yet Distinct Unconscious States in the MedullaR35GM151166 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI Toshihiro Imamura · 2023 to 2026
$1.6M
NIGMS NIH HHS R01 GM144377NIGMS NIH HHS R01 GM151556NIGMS NIH HHS R35 GM151166
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID40067034
PMCPMC12282489

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.