Evidence map›Paper›PMID 40066944›Full record

ReviewAmerican journal of hematology2025

TP53 -Mutated Myeloid Neoplasms: 2024 Update on Diagnosis, Risk-Stratification, and Management.

Mithun Vinod Shah, Daniel A Arber, Devendra K Hiwase

Abstract readReview
In one paragraph

Review in American journal of hematology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Trial
  2. Review
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  5. Lenalidomide Exposure andCurrent oncology (Toronto, Ont.) · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
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  16. Antigen-directed p53 restoration inFrontiers in oncology · 2026
    Article
  17. Article
  18. Article
  19. Article
  20. Pandora's Box of AML: HowBiomedicines · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mithun Vinod ShahDivision of Hematology, Mayo Clinic, Rochester, Minnesota, USA.ORCID 0000-0002-5359-336X
Daniel A ArberDepartment of Pathology, University of Chicago, Chicago, Illinois, USA.ORCID 0000-0002-2160-9689
Devendra K HiwaseDepartment of Haematology, Royal Adelaide Hospital, Central Adelaide Local Health Network, Adelaide, South Australia, Australia.ORCID 0000-0002-6666-3056

Funding

AbbVieAstellas PharmaBristol Myers Squibb/CelgeneKURA Oncology, Inc.Marker Therapeutics
6 · The paper itself

Abstract

Alterations in the tumor suppressor gene TP53 are common in human cancers and are associated with an aggressive nature. Approximately 8%-12% of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) harbor TP53 mutations (TP53

Indexed as

Leukemia, Myeloid, AcuteMutationMyelodysplastic SyndromesTumor Suppressor Protein p53Disease ManagementHumansRisk AssessmentTP53 protein, humanTumor Suppressor Protein p53AML—molecular diagnosis & therapymyelodysplastic syndromeneoplasia—myeloid leukemias and dysplasiasp53

Identifiers

PMID40066944
PMCPMC12067166

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.