Evidence map›Paper›PMID 40066649›Full record

SynthesisThe Laryngoscope2025

Suicidal Ideation and Behaviors in Adults With Tinnitus: A Systematic Review and Meta-Analysis.

Lauren R McCray, Megan K Scharner, Shaun A Nguyen, Habib G Rizk, Ted A Meyer, Robert F Labadie, Thomas W Uhde, Peter R Dixon

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in The Laryngoscope, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Suicidality in Individuals With Hearing Loss: A Systematic Review and Meta-Analysis.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2026
    Pooled it
  2. Article
  3. Article
  4. Tinnitus.Nature reviews. Disease primers · 2026
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lauren R McCrayDepartment of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina, USA.ORCID 0009-0005-2700-2721
Megan K ScharnerDepartment of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina, USA.
Shaun A NguyenDepartment of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina, USA.ORCID 0000-0003-0664-4571
Habib G RizkDepartment of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina, USA.ORCID 0000-0002-3902-6203
Ted A MeyerDepartment of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina, USA.
Robert F LabadieDepartment of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina, USA.
Thomas W UhdeDepartment of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, South Carolina, USA.
Peter R DixonDepartment of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina, USA.ORCID 0000-0002-3537-5078

Funding

Interdisciplinary Research Training in Otolaryngology and Communication SciencesT32DC014435 · NIDCD · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI DUBNO, JUDY R · 2015 to 2024
$2.9M
NIDCD NIH HHS T32 DC014435
6 · The paper itself

Abstract

objectiveTo assess relations between tinnitus and suicidality, measured by suicidal ideation and suicide attempts. DATA SOURCES: CINAHL, Cochrane Library, PubMed, PsycINFO, and SCOPUS databases were searched from inception through June 14, 2024. REVIEW

methodsObservational studies related to suicidality in tinnitus patients at least 18 years old were included. Case reports and studies on objective or pulsatile tinnitus were excluded. Two authors extracted data, and disagreements were resolved with a third party if needed. The risk of bias was assessed according to the Risk Of Bias In Non-randomized Studies of Exposure for cohort studies and the Joanna Briggs Institute critical appraisal checklist for cross-sectional studies. Random effects meta-analyses (single means, proportions, and relative risks (RR)) were used for primary analysis.

resultsNine studies (n = 912,013) pertaining to suicidality and tinnitus in an adult population were included. The tinnitus group experienced a significantly higher prevalence of suicidal ideation (19.5% [95% CI: 12.9%-27.1%] versus 9.9% [95% CI: 7.1%-13.2%]) and suicide attempts (1.9% [95% CI: 0.1%-5.7%] versus 0.9% [95% CI: 0.0%-3.9%]) than the control population (p < 0.0001). The tinnitus group had a significantly (p < 0.001) higher risk of suicidal ideation (RR = 2.1, 95% CI: 1.6-2.8) and suicide attempts (RR = 1.8, 95% CI: 1.3-2.4) than the control group.

conclusionNearly one in five people with tinnitus will experience suicidal ideation, and nearly 2% will attempt suicide. Thus, otolaryngologists should be mindful of the increased risk of suicidality in patients with tinnitus.

Indexed as

Suicidal IdeationSuicide, AttemptedTinnitusAdultHumansPrevalencemeta‐analysisquality of lifesystematic reviewtinnitus

Identifiers

PMID40066649
PMCPMC13170513

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.