Evidence map›Paper›PMID 40066346›Full record

ArticleIJID regions2025

Burden of rotavirus and other microorganisms in hospitalized children with acute gastroenteritis in Yangon, Myanmar, before the introduction of rotavirus vaccine.

Tatsuki Ikuse, Yuta Aizawa, Kazuhiro Kamata, Khin Nyo Thein, Di Ja Lasham, Su Sandar Tun, Nay Chi Win, Su Mon Kyaw Win, Ai Ito, Mon Mon and 8 more

Abstract read
In one paragraph

Article in IJID regions, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Tatsuki IkuseDepartment of Pediatrics, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Yuta AizawaDepartment of Pediatrics, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Kazuhiro KamataDepartment of Pediatrics, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Khin Nyo TheinYankin Children Hospital, Yangon, Myanmar.
Di Ja LashamInfectious Diseases Research Centre of Niigata University in Myanmar, Yangon, Myanmar.
Su Sandar TunInfectious Diseases Research Centre of Niigata University in Myanmar, Yangon, Myanmar.
Nay Chi WinInfectious Diseases Research Centre of Niigata University in Myanmar, Yangon, Myanmar.
Su Mon Kyaw WinInfectious Diseases Research Centre of Niigata University in Myanmar, Yangon, Myanmar.
Ai ItoDepartment of Pediatrics, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Mon MonDepartment of Microbiology, University of Medicine 2, Yangon, Myanmar.
Aye ThidaDepartment of Medical Education, University of Medicine 2, Yangon, Myanmar.
Aye Aye KhinRector, University of Medicine 2, Yangon, Myanmar.
Yuki HigashimotoFaculty of Cellular and Molecular Biology, Fujita Health University School of Medical Sciences, Toyoake, Japan.
Tetsushi YoshikawaDepartment of Pediatrics, Fujita Health University School of Medicine, Toyoake, Japan.
Satoshi KomotoDepartment of Virology, Fujita Health University School of Medicine, Toyoake, Japan.
Hisami WatanabeInfectious Diseases Research Centre of Niigata University in Myanmar, Yangon, Myanmar.
Reiko SaitoDivision of International Health, Graduate School of Medical and Dental Science, Niigata University, Niigata, Japan.
Akihiko SaitohDepartment of Pediatrics, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: In developing countries, acute gastroenteritis (AGE) is a leading cause of death in children younger than 5 years. In Myanmar, no comprehensive study has been done to investigate the microorganisms responsible for AGE among hospitalized children. Multiplex polymerase chain reaction (PCR) was used to identify the microorganisms responsible for AGE in children hospitalized in Myanmar before the introduction of the rotavirus vaccine. Methods: This prospective study enrolled children younger than 12 years with AGE who were hospitalized at the Yankin Children's Hospital in Yangon, Myanmar, between September 2019 and February 2020. Multiplex PCR (FilmArray Results: We collected stool samples from 92 patients. Multiple microorganisms (median 3; interquartile range 2-4) were detected in 81 patients (88%). Rotavirus and norovirus were detected in 77 (84%) and 33 patients (36%), respectively. The most frequent bacterial pathogen detected was Enteroaggregative Conclusions: Rotavirus is the predominant pathogen associated with AGE in hospitalized children in Myanmar. The introduction of a rotavirus vaccine will reduce the morbidity and mortality of children with rotavirus-associated AGE in Myanmar.

Indexed as

Acute gastroenteritisChildrenMyanmarPCRRotavirus

Identifiers

PMID40066346
PMCPMC11891738

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.