ArticleFrontiers in pharmacology2025
Structural analysis and treatment of acute liver injury of polysaccharides from the
Article in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- From genomics to horticultural innovation: botanical traits, bioactive compounds, and sustainable utilization of kiwifruit (Frontiers in plant science · 2026Review
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To investigate the therapeutic effects of the PRAC on acute liver injury and its potential as an ingredient in drugs and nutraceuticals. Methods: Microwave-assisted extraction technology combined with Box-Behnken model combined with the three kinds of artificial neural networks was used to optimize PRAC extraction process. Characterize the structure and composition of PRAC. In order to prevent PRAC from being degraded by the gastrointestinal environment, PRAC-loaded liposomes were fabricated. The efficacy of PRAC-loaded liposomes was evaluated by three acute liver injury animal models prepared according to different mechanisms. Results: The best yield of PRAC was 4.49%, and the purity reached up to 86.53% by optimizing the microwave parameters using Box-Behnken model combined with the three kinds of artificial neural networks. PRAC was characterized as a galactan having a backbone consisting predominately of →4)-D-Gal Conclusion: PRAC is a potential drug for the treatment of acute liver injury.
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