Evidence map›Paper›PMID 40066313›Full record

ArticleFrontiers in neurology2025

Association of ADHD and LD with vision abnormalities among the children and adolescents in US, NHANES 1999-2004.

Jiamin Lu, Kefan Zhou, Yingyu Liang, Qishan Li, Jiawen Zhong, Xia Zeng, Tianran Shen, Chongzhen Sun, Xinping Yu, Jinhua Lu and 1 more

Abstract read
In one paragraph

Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jiamin Lu *Department of Child and Adolescent Health, School of Public Health, Guangdong Pharmaceutical University, Guangzhou, China.
Kefan Zhou *Department of Child and Adolescent Health, School of Public Health, Guangdong Pharmaceutical University, Guangzhou, China.
Yingyu LiangDepartment of Child and Adolescent Health, School of Public Health, Guangdong Pharmaceutical University, Guangzhou, China.
Qishan LiDepartment of Child and Adolescent Health, School of Public Health, Guangdong Pharmaceutical University, Guangzhou, China.
Jiawen ZhongDepartment of Child and Adolescent Health, School of Public Health, Guangdong Pharmaceutical University, Guangzhou, China.
Xia ZengDepartment of Child and Adolescent Health, School of Public Health, Guangdong Pharmaceutical University, Guangzhou, China.
Tianran ShenDepartment of Nutrition and Food Health, School of Public Health, Guangdong Pharmaceutical University, Guangzhou, China.
Chongzhen SunDepartment of Nutrition and Food Health, School of Public Health, Guangdong Pharmaceutical University, Guangzhou, China.
Xinping YuState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, China.
Jinhua LuDivision of Birth Cohort Study, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
Wenhan YangDepartment of Child and Adolescent Health, School of Public Health, Guangdong Pharmaceutical University, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To examine the association of ADHD and LD with visual impairment, uncorrected refractive error, and refractive error (myopia, hyperopia, and astigmatism) among US children and adolescents. Method: A population-based cross-sectional study included 3,385 participants aged 12-15 years from the large, representative sample of US NHANES. The diagnoses of ADHD and LD in children and adolescents, as reported by parents or adolescents themselves, were analyzed. All participants' right eyes were used to calculate the spherical equivalent refractive errors (SER) during the investigation. Myopia, hyperopia, and astigmatism were classified by SER. Visual acuity was categorized into normal, uncorrected refractive error (URE), and visual impairment (VI) according to objectively assessed for each eye. Logistic regression analysis was used to estimate the associations between ADHD and LD and vision abnormalities. Results: Among a total of 3,385 children and adolescents aged 12-15 years, 279 were reported to have a diagnosis of ADHD, and 427 were reported to have a diagnosis of LD. Compared with those without ADHD, children and adolescents with ADHD had an increased risk of hyperopia, with odds ratios (ORs) of 1.66 (95% CI, 1.03-2.67). LD was associated with higher risks of hyperopia (OR = 1.85, 95% CI, 1.17-2.90) and astigmatism (OR = 1.63, 95% CI: 1.18-2.26). After controlling for confounding variables, the results remained stable. LD also increased the risk of vision impairment (OR = 3.05, 95% CI: 1.05-8.90) after controlling for confounders. Stratified analyses showed that ADHD was a risk factor for hyperopia in boys compared with girls (OR = 1.62, 95%CI = 1.03-2.72), in 12-13-year-old individuals compared with 14-15-year-olds (OR = 1.69, 95%CI = 1.05-3.42). LD was a risk factor for hyperopia and astigmatism in girls compared with boys (OR = 2.81, 95%CI = 1.53-5.14; OR = 2.18, 95%CI = 1.22-3.90), and in 12-13-year-old individuals compared with 14-15-year-olds (OR = 1.99, 95%CI = 1.16-3.42; OR = 1.65, 95%CI = 1.07-2.56). Conclusion: Children and adolescents diagnosed with ADHD and LD may be at a greater risk of developing hyperopia and astigmatism. To accurately diagnose and treat children affected by ADHD and LD, healthcare practitioners from various medical specialties should take this association into account.

Indexed as

ADHDattention-deficit/hyperactivity disorderlearning disabilitiesrefractive errorvision

Identifiers

PMID40066313
PMCPMC11891056

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.