ReviewFrontiers in microbiology2025
Biodegradation of polyhydroxyalkanoates: current state and future prospects.
Review in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Polyhydroxyalkanoate degradation in soils: mechanisms, controls, biological responses, and knowledge gaps.Frontiers in microbiology · 2026Pooled it
- Microbial synthesis and degradation of bio-based biodegradable plastics.Nature reviews. Microbiology · 2026Review
- Mechanistic insights into the degradation of poly (3-hydroxybutyrate) and its copolymers by Nocardiopsis dassonvillei NCIM 5124.Molecular biology reports · 2026Article
- Biodegradable Polyhydroxyalkanoates as Advanced Antimicrobial Biomaterials: A Review.Biotechnology and bioengineering · 2026Review
- Functional dynamics and interactions within the bacterial community responsible for biodegradable plastic degradation during aerobic composting.Biodegradation · 2026Article
- Sustainable P3HB:ZnO Composite Piezoelectric Nanofibers for AI-Driven Gait Monitoring.Small science · 2026Article
- Polyhydroxybutyrate (PHB): Production, Properties, Modification Strategies, Additive Manufacturing, Biodegradation, and Applications.Materials (Basel, Switzerland) · 2026Review
- Plastic-Degrading Microorganisms: Biodegradation Pathways and Habitat Origins.Molecules (Basel, Switzerland) · 2026Review
- Investigating the Durability of PHA-Coated Burlap for Coastal Restoration.ACS applied engineering materials · 2026Article
- Draft-genome sequence ofMicrobiology resource announcements · 2026Article
- Unlocking the Potential of Macroalgae: Innovative Pretreatment Strategies for Efficient Biorefinery.Molecules (Basel, Switzerland) · 2026Review
- Toward Greener Multilayer Packaging Material Solutions Based on Microbial Protein and Polyhydroxyalkanoate.ACS applied engineering materials · 2026Article
- Advances in Polyhydroxyalkanoate (PHA) Production, Volume 4.Bioengineering (Basel, Switzerland) · 2026Article
- Article
- Sustainable Production of Poly(3-hydroxybutyrate) Using Eucalyptus Bark: Integration with Green Downstream Processing.ACS sustainable chemistry & engineering · 2026Article
- The Diversity of Plastisphere Bacterial and Fungal Communities Differs between Biodegradable Polymer Types in Soil.Microbial ecology · 2026Article
- A novel polyhydroxyalkanoate-storing bacterium Thauera carbonocopians sp. nov. isolated from a sequencing batch reactor fed with volatile fatty acids.Scientific reports · 2026Article
- Homogeneous Crystal Nucleation of Poly(3-hydroxybutyrate): Kinetics, Stability, and Cluster-Size Distribution.Macromolecules · 2026Article
- From Waste to Treasure: Therapeutic Horizons of Polyhydroxyalkanoates in Modern Medicine.Pharmaceutics · 2026Review
- Metagenomic insights into microbial diversity, xenobiotic and plastic-degrading enzymes in sediments of river Yamuna at Agra.Frontiers in microbiology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Polyhydroxyalkanoates (PHAs) are biobased and biodegradable polymers that offer a sustainable alternative to conventional plastics, addressing the escalating concerns over plastic pollution. While their environmental advantages are well-documented, the efficient degradation of PHAs in natural and engineered environments remains a critical component of their lifecycle. This review provides a comprehensive overview of PHA-degrading bacteria isolated from diverse ecosystems and highlights the pivotal role of PHA depolymerases in achieving PHA circularity. Microbial adaptation to diverse environmental conditions, such as extreme temperatures, salinity, and pH, significantly influences enzymes properties, including the stability, activity, and substrate specificity of PHA-degrading enzymes. These adaptations often enhance enzyme, performance, enabling functionality under challenging conditions. Consequently, extremophilic microorganisms are invaluable resources for discovering and engineering robust PHA depolymerases for industrial and environmental applications. This review underscores the urgent need for further research to improve the ecological and economic sustainability of PHA waste management.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.