Evidence map›Paper›PMID 40066227›Full record

ArticleMedComm2025

Carabrone Attenuates Metabolic Dysfunction-Associated Steatohepatitis by Targeting STAT3 in Mice.

An Pan, Jiaming Jin, Yuze Wu, Qiang Zhang, Huanhuan Chen, Yang Hu, Wen Xiao, Anqi Shi, Yang Yang, Lina Jiang and 3 more

Abstract read
In one paragraph

Article in MedComm, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Frontiers in pharmacology · 2026
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

An PanState Key Laboratory on Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture Nanjing University of Chinese Medicine Nanjing China.
Jiaming JinJiangsu Key Laboratory for Functional Substance of Chinese Medicine School of Pharmacy Nanjing University of Chinese Medicine Nanjing China.
Yuze WuJiangsu Key Laboratory for Functional Substance of Chinese Medicine School of Pharmacy Nanjing University of Chinese Medicine Nanjing China.
Qiang ZhangJiangsu Key Laboratory for Functional Substance of Chinese Medicine School of Pharmacy Nanjing University of Chinese Medicine Nanjing China.
Huanhuan ChenJiangsu Key Laboratory for Functional Substance of Chinese Medicine School of Pharmacy Nanjing University of Chinese Medicine Nanjing China.
Yang HuJiangsu Key Laboratory for Functional Substance of Chinese Medicine School of Pharmacy Nanjing University of Chinese Medicine Nanjing China.
Wen XiaoJiangsu Key Laboratory for Functional Substance of Chinese Medicine School of Pharmacy Nanjing University of Chinese Medicine Nanjing China.
Anqi ShiJiangsu Key Laboratory for Functional Substance of Chinese Medicine School of Pharmacy Nanjing University of Chinese Medicine Nanjing China.
Yang YangJiangsu Key Laboratory for Functional Substance of Chinese Medicine School of Pharmacy Nanjing University of Chinese Medicine Nanjing China.
Lina JiangJiangsu Key Laboratory for Functional Substance of Chinese Medicine School of Pharmacy Nanjing University of Chinese Medicine Nanjing China.
Minghui TanJiangsu Key Laboratory for Functional Substance of Chinese Medicine School of Pharmacy Nanjing University of Chinese Medicine Nanjing China.
Junwei WangState Key Laboratory on Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture Nanjing University of Chinese Medicine Nanjing China.
Lihong HuJiangsu Key Laboratory for Functional Substance of Chinese Medicine School of Pharmacy Nanjing University of Chinese Medicine Nanjing China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metabolic dysfunction-associated steatohepatitis (MASH) has become one of the most common progressive liver diseases worldwide, but effective treatment options are severely unmet. Carabrone, a sesquiterpene lactone from the traditional Chinese herb

Indexed as

carabronechemoproteomic profilingMASHSTAT3

Identifiers

PMID40066227
PMCPMC11892021

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.