ArticleInternational journal of women's health2025
Global Trends in Incidence and Mortality Rates of Endometrial Cancer Among Individuals Aged 55 years and Above From 1990 to 2021: An Analysis of the Global Burden of Disease.
Article in International journal of women's health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic review of immune checkpoint inhibitors in endometrial cancer.Frontiers in oncology · 2026Pooled it
- Evaluation of Punicalagin as a multi‑targeted therapeutic agent against endometrial cancer.International journal of oncology · 2026Article
- E7386 plus lenvatinib in patients with advanced endometrial cancer that progressed on platinum-based chemotherapy and an anti-PD-(L)1 immunotherapy: a single-arm, open-label, global phase 1b/2 dose-expansion cohort.EClinicalMedicine · 2026Article
- Diabetes mellitus and risk of endometrial cancer: an updated systematic review and meta-analysis.Acta diabetologica · 2026Review
- A nomogram for predicting high-risk endometrial cancer based on the transvaginal ultrasonography and contrast-enhanced ultrasonography.Quantitative imaging in medicine and surgery · 2026Article
- A Retrospective Cohort Study of Uterine Cancer Epidemiological Analysis and Age-Based Disparities in Saudi Arabian Population across 32 Years.Saudi medical journal · 2026Article
- Effects of adjuvant propofol on antitumoral effects of carboplatin in experimental endometrial cancer: possible epigenetic associations.Scientific reports · 2026Article
- Natural Products in Endometrial Cancer: Molecular Mechanisms, Preclinical Evidence, and Clinical Perspectives.Current issues in molecular biology · 2026Review
- High expression of the ADC target Claudin-6 associates with aggressive endometrial cancer and remains high in metastatic lesions.BJC reports · 2026Article
- Endometrial cancer mortality and its trends in China from 2004-2021.BMC cancer · 2026Article
- Endometriosis and Endometrial Cancer-Association Between Biological Mechanisms and Its Clinical Implications.Journal of clinical medicine · 2026Review
- Cytostatic and Non-Apoptotic Effects of Vinorelbine-Based Therapy in 3D Endometrial Cancer Spheroids.Biology · 2026Article
- Article
- The Association Between Cadmium Exposure and Endometrial Cancer Risk: Evidence from a Comprehensive Updated Meta-Analysis.Journal of clinical medicine · 2026Review
- Quantitative Texture Analysis of Cervical Cytology Identifies Endometrial Lesions in Atypical Glandular Cells on Liquid-Based Cytology: A Pilot Study.Diagnostics (Basel, Switzerland) · 2026Article
- The International Gynecologic Cancer Society Global Fellowship Program: advancing access to gynecologic oncology and surgical care worldwide.International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · 2026Article
- Prognostic Factors in the Treatment of Advanced Endometrial Cancer Patients: 12-Year Experience of an ESGO Certified Center.Cancers · 2026Article
- Global, regional, and national burden of ovarian cancer and uterine cancer attributable to high BMI, 1990-2021: analysis of data from the global burden of disease study 2021.Frontiers in oncology · 2026Article
- Prognostic and predictive roles of microsatellite instability and mismatch repair deficiency in early-stage endometrial cancer: a structured narrative review.Obstetrics & gynecology science · 2026Review
- Critical role of reproductive tract microbiota and derived metabolites in inflammation, tumor immunity, and tumorigenesis of gynecological cancers: a narrative review.Frontiers in immunology · 2026Review
Corrections and comments
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5 authors.
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Abstract
Purpose: To describe the temporal trend of endometrial burden in postmenopausal women aged 55 years and above worldwide from 1990 to 2021, evaluate the age cohort effect, explore its influencing factors, and predict the disease burden in the next 15 years. Patients and Methods: Using Joinpoint regression, data from the 2021 Global Burden of Disease Study were assessed for changes in endometrial cancer incidence rate, morbidity, and mortality in postmenopausal women aged 55 years and above. Age period cohort analysis helped estimate age, period, and cohort effects. The Das Gupta method helped analyze effects of different factors on endometrial cancer incidence and mortality among postmenopausal patients. ARIMA helped predict the endometrial cancer disease burden in postmenopausal women from 2022 to 2036. Results: In 2021, globally, there were 360253 (326,176-388545) cases and 84630 (75,523-93215) deaths among postmenopausal patients with endometrial cancer. During 1990-2021, the global endometrial cancer incidence in postmenopausal women gradually increased, while the mortality rate gradually decreased. Changes in disease incidence and mortality rates are mainly due to population growth and epidemiological changes, with little influence of age. The risk of endometrial cancer in postmenopausal women gradually increased with age, using age, period, and cohort average as the reference groups. The mortality rate decreased gradually decreased in 2019 and continued to rise thereafter. It is expected that by 2036, the incidence of endometrial cancer in postmenopausal women aged 55 years and above will increase by 6.5%, and the mortality rate will decrease by 8.0%. Conclusion: The number of patients with postmenopausal endometrial cancer aged 55 years and above is still increasing, and it is necessary to establish a comprehensive screening and treatment mechanism to ensure prolongation of patient lifespan.
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