Evidence map›Paper›PMID 40066055›Full record

ArticleHeliyon2025

Biomechanical assessment of unilateral/bilateral lumbar spondylolysis with and without muscle weakness using finite element analysis.

Baiyang Ding, Kazuhiro Imai, Zhuo Chen, Liang Xiao

Abstract read
In one paragraph

Article in Heliyon, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Baiyang DingDepartment of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo, Komaba, Meguro-ku, Tokyo, Japan, 3-8-1, Komaba, Meguro-ku, Tokyo, 153-8902, Japan.
Kazuhiro ImaiDepartment of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo, Komaba, Meguro-ku, Tokyo, Japan, 3-8-1, Komaba, Meguro-ku, Tokyo, 153-8902, Japan.
Zhuo ChenDepartment of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo, Komaba, Meguro-ku, Tokyo, Japan, 3-8-1, Komaba, Meguro-ku, Tokyo, 153-8902, Japan.
Liang XiaoSpine Research Center of Wannan Medical College, Wuhu, China, 22, Wenchang West Road, China, Wuhu, 241001, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Spondylolysis is commonly linked to low back pain in athletes, and the connection between muscle weakness and spondylolysis is unclear. Therefore, this study examined the biomechanics of spondylolysis and influence of muscle weakness by finite element (FE) analysis. Methods: A patient's L1-S1 lumbosacral unit was scanned by computed tomography, and generated a three-dimensional pathology-free FE model. Unilateral incomplete, unilateral, and bilateral defect models of the L5 isthmus were created. The mobility of the sacrum was limited to 7.5 N m moment, and a 500 N load was applied to the top of the L1 to simulate the human weight. The loading conditions included flexion, extension, bending, and axial torsion. Muscle forces representing the global back muscles and abdominal muscles, follower loads, and body weight were added to the FE model. The force of the global back muscles was decreased to 50 % to simulate back muscle weakness. Findings: The result shows that the L5 vertebral body in unilateral incomplete lumbar spondylolysis exhibited the greatest range of motion during flexion. The L5 vertebral body in unilateral lumbar spondylolysis demonstrated increased mobility during flexion and right torsion. The reduction of muscle strength led to the range of motion of L5 being reduced in all motions, but the maximum principal stress did not change significantly. However, the range of motion and maximum principal stress of L4 increased, especially in the bilateral group. Interpretations: From a biomechanical perspective, this study indicates that unilateral incomplete spondylolysis and unilateral spondylolysis might worsen during different motions. The reduction of muscle strength can cause spondylolysis to spread to adjacent segments and further worsen. A decrease in muscle force led to a decrease in the range of motion in the lumbar spondylolysis defect, but it also led to an increase in the range of motion in the adjacent segments.

Identifiers

PMID40066055
PMCPMC11891713

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.