ArticleIndian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India2025
Refractory Secondary Hyperparathyroidism in Chronic Renal Impairment: Is Surgery a Viable Option to Achieve a Biochemical Balance in Patients Failing Medical Management?
Article in Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Abstract
Secondary hyperparathyroidism (SHPT) is a common complication in chronic kidney disease patients, necessitating effective management to prevent adverse outcomes. This study evaluates the efficacy of surgical intervention in achieving biochemical balance in SHPT patients resistant to medical therapy. The study includes 36 patients with SHPT who underwent subtotal parathyroidectomy following failed medical management. Surgical outcomes, postoperative complications, and long-term follow-up data are analyzed. Of the total patients, 23 patients (63.9%) experienced symptomatic hypocalcaemia and 14 patients (38.9%) had hungry bone syndrome (HBS). The average time to calcium nadir in the post-op period was 75 hours (52-84 hours). The average length of the hospital stay was five days. A total of 5 patients (13.8%) had post-op nerve palsies. Our cohort had an initial cure rate of 91.6% with only 3 patients (8.3%) detected to have persistent hypercalcemia post-procedure. Even in the above, remnant or ectopic parathyroid glands were detected on follow-up imaging and subjected to re-surgery, which resulted in a cure. A statistically significant fall in mean PTH (
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